Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
Conditions
Keywords
Pregancy, Iron deficiency, Anemia
Brief summary
During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth. Around half of pregnant women develop anemia, and after delivery, up to 85% of women may be affected. This study looks at whether iron given through a vein (intravenous iron) can improve blood levels and how women feel and function in everyday life before and after giving birth.
Interventions
DRUGIron
Iron supplementation will be performed according to Hamza et al., Recommendations of the AGG (Obstetrics Working Group, Section for Maternal Diseases) for the Management of Anemia in Pregnancy - Part 1 (Iron Deficiency Anemia) (https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-2628-7308.pdf)
Sponsors
Johann Wolfgang Goethe University Hospital
Wuerzburg University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Pregnancy
Exclusion criteria
* Thalassemia * Sickle cell disease * Aplastic anemia * Hemochromatosis * Chronic inflammatory diseases associated with anemia of chronic disease * Severe renal insufficiency * Intravenous iron administration within 3 months prior to enrollment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of patients achieving an increase in hemoglobin concentration of ≥1 g/dL | between iron supplementation and follow-up: 2-4 weeks | Proportion of patients with an increase in hemoglobin concentration of ≥1 g/dL from before the first intravenous iron administration to the last available measurement before delivery |
Countries
Germany
Contacts
CONTACTSuma Choorapoikayil, PhD
CONTACTPatrick Meybohm, MD
Outcome results
None listed