Clinical Evaluation of Zirconium Dioxide Nano-Coated Arch Wires

Assessment of the Role of Zirconium Dioxide Nanocoating of Arch Wires on the Rate of Orthodontic Tooth Movement During Leveling and Alignment: A Comparative Clinical Study

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07813117

Enrollment

Registered

2026-09-10

Start date

2026-09-01

Completion date

2028-09-01

Last updated

2026-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion of Anterior Teeth

Brief summary

"This clinical trial aims to evaluate the clinical performance and efficiency of zirconium dioxide nano-coated orthodontic archwires compared to conventional archwires. The study focuses on assessing the leveling and alignment duration, as well as evaluating patient comfort and clinical outcomes during the initial stages of orthodontic treatment."

Interventions

DEVICEZirconium dioxide nano-coated archwire

Zirconium dioxide nano-coated nickel-titanium archwire used during the leveling and alignment phase of fixed orthodontic treatment, compared against conventional uncoated NiTi archwires."

DEVICEConventional orthodontic archwire

Conventional orthodontic archwire used during the leveling and alignment phase of fixed orthodontic treatment, compared against Zirconium dioxide nano-coated nickel-titanium archwire

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

13 Years to 19 Years

Healthy volunteers

Inclusion criteria

* Participants within the age range of 13 to 19 years. * Moderate crowding (4-6 mm) in the maxillary anterior segment, evaluated using the Little Irregularity Index (LII), indicating the need for treatment with a fixed appliance without extractions. * Patients in permanent dentition with all teeth had fully erupted ( excluding 3rd molars) * Good oral hygiene. * No previous orthodontic treatment.

Exclusion criteria

* Transverse and/or vertical skeletal dysplasia or craniofacial malformation * Retained primary or missing permanent teeth in the maxillary anterior area. * Present or history of periodontal diseases. * Physical or mental disability. * Systemic diseases or regular use of medications that could interfere with orthodontic tooth movement.

Design outcomes

Primary

Measure	Time frame	Description
Rate of dental alignment	Measured at baseline and every 4 weeks up to 16 weeks .	Little's Irregularity Index (unabbreviated scale title). The index measures the linear displacement of the five anatomic points of the anterior teeth. Scores range from a minimum of 0 (representing perfect alignment with no displacement) to a maximum of 10 or higher (representing severe dental crowding and irregularity). Lower scores indicate a better outcome (greater dental alignment and successful leveling phase).

Contacts

CONTACTMohamed E Desoky, postgraduate student

mohameddosoky757@gmail.com+201020353336

STUDY_DIRECTORRaafat E Mohamed, Professor

Al-Azhar University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 11, 2026