Management of Arachnoid Nerve Tethering in Trigeminal Neuralagia

Management of arachnoid_nerve Tethering in Trigeminal Neuralgia

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07811973

Enrollment

Registered

2026-09-10

Start date

2026-08-31

Completion date

2028-09-30

Last updated

2026-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trigeminal Neuralgia

Brief summary

This study aims to evaluate the clinical significance of arachnoid-trigeminal nerve conflict in patients with medically refractory trigeminal neuralgia without demonstrable neurovascular conflict on preoperative magnetic resonance imaging (MRI). Patients undergoing surgical exploration will be assessed clinically, radiologically, and intraoperatively for the presence and characteristics of arachnoid adhesions or tethering involving the trigeminal nerve. Endoscopic-assisted arachnoid release will be performed when appropriate. Postoperative pain outcome will be evaluated using the Barrow Neurological Institute (BNI) pain intensity score and the Visual Analog Scale (VAS). Recurrence, postoperative complications, MRI-intraoperative correlation, and potential predictors of favorable surgical outcome will also be evaluated.

Interventions

PROCEDUREArachnoid nerve detethering

Endoscopic assisted

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Age more 18 * Failed medical treatment

Exclusion criteria

* Vascular compression * Tumors

Design outcomes

Primary

Measure	Time frame	Description
Bni (Barrow Neurological Institute) score improvement	2years	Pain free without medication

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 11, 2026