China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial Aneurysm

Treatment Strategies for Tumor in Sellar Region With Unruptured Intracranial Aneurysms in the Chinese Population

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07809178

Acronym

ChTTSRUIA

Enrollment

608

Registered

2026-09-09

Start date

2026-09-01

Completion date

2031-09-01

Last updated

2026-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chordoma, Craniopharyngioma, Germinoma, Hypothalamic Neoplasms, Meningioma, Optic Pathway Glioma, Pituitary Neuroendocrine Tumor, Rathke Cleft Cysts, Unruptured Intracranial Aneurysms

Keywords

Tumor in sellar region, Unruptured intracranial aneurysms

Brief summary

The goal of this observational study is to learn about the treatment strategies for tumor in sellar region with unruptured intracranial aneurysms in the Chinese population. The main question it aims to answer is: For patients with tumor in sellar region combined with unruptured intracranial aneurysms, which condition should be treated first?

Detailed description

The goal of this observational study is to clarify the treatment strategies for tumor in sellar region with unruptured intracranial aneurysms in the Chinese population aged from 18 to 75. The main question it aims to answer is: * What is the appropriate treatment strategy for patients diagnosed with tumor in sellar region with unruptured intracranial aneurysms? * Should the tumor be resected first followed by aneurysm treatment, or should the aneurysm be treated prior to tumor resection? Alternatively, is tumor resection alone with regular observation of the aneurysm a viable option? * What are the patient's intraoperative risks, postoperative complications, and prognosis? Participants are required to: * Provide detailed medical records. * Complete laboratory tests and imaging examinations at scheduled time points and cooperate with neurosurgeons for follow-up visits after the relevant treatments. This is an observational study. It solely collects patients' pre-operative, intra-operative, and post-operative follow-up information and does not influence the patient's treatment process or clinical decision-making.

Interventions

PROCEDURETumor resection followed by aneurysm treatment

Tumor resection followed by aneurysm treatment

PROCEDUREAneurysm treatment followed by tumor resection

Aneurysm treatment followed by tumor resection

OTHERObservation

Tumor resection without aneurysm treatment but observation

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

1. Preoperative enhanced head MRI showing a suspected diagnosis of a sella region lesion, and preoperative head CTA/DSA confirming an unruptured intracranial aneurysm. 2. Patients with primary sella region tumor and unruptured intracranial aneurysms that have not previously accepted surgical treatment. 3. Patients with tumor in sellar region requiring craniotomy or endoscopic transnasal surgery and/or an aneurysm requiring craniotomy, endovascular treatment, or observation only. 4. The patients are in good general health, without severe underlying medical conditions, and capable of tolerating surgical treatment. 5. Patients or their legal guardians have signed an informed consent form and voluntarily agreed to participate in the clinical trial.

Exclusion criteria

1. Patients with recurrent sella region tumors. 2. Patients with previously treated intracranial aneurysm. 3. Pregnant or breastfeeding women. 4. Any other condition that, in the investigator's judgment, makes the patient unsuitable for trial participation.

Design outcomes

Primary

Measure	Time frame	Description
Aneurysm progression	From enrollment to the end of treatment at 24 months	The diameter of aneurysm neck, the diameter of aneurysm dome, the volume of aneurysm, aneurysm rupture status
Tumor related complication and progression	From enrollment to the end of treatment at 24 months	The related complication and progression of tumor in sellar region: pituitary hormone level, visual acuity and visual field, hydrocephalus and tumor recurrence.

Countries

China

Contacts

CONTACTSen Cheng, MD

dr.sencheng@hotmail.com+8615313520109

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 10, 2026