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Individual Narratives of Stimulation (ECT and TMS)

Lived Experience of People Who Have Received Both Electroconvulsive Therapy (ECT) and Transcranial Magnetic Stimulation (TMS) for Treating Major Depressive Disorder: a Narrative Inquiry

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07807930
Acronym
INSight
Enrollment
12
Registered
2026-09-08
Start date
2026-11-01
Completion date
2027-10-31
Last updated
2026-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depression

Keywords

Narrative inquiry, Qualitative interviews, Transcranial magnetic stimulation (TMS), Electroconvulsive therapy (ECT), Lived experience

Brief summary

Electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are two evidence-based treatments for major depressive disorder. Both work by stimulating the brain (a process known as neuromodulation), but they differ markedly in invasiveness. ECT requires a general anaesthetic, whereas TMS is delivered while a person is awake and alert and they can go home immediately afterwards. TMS has been proposed as an alternative to ECT for some people. However, TMS is not as effective as ECT in all cases, is generally slower acting, and remains less widely available. In Nottingham and Liverpool, we have identified a small number of individuals who have experienced both ECT and TMS across different episodes of depression. One such individual is a lived experience co-researcher on our team. Whilst previous studies have explored experiences of ECT and TMS separately, often using relatively superficial methods, none have examined the perspectives of people who have received both treatments. This study addresses that gap through an in-depth exploration of their experiences. We will use a narrative inquiry approach that encourages participants to tell the story of their experiences of ECT and TMS in their own words. Eligible participants will be adults who have previously received both treatments for depression. Participation involves four sessions: a structured discussion to map the timeline of their depression and treatments, two in-depth open-ended interview sessions (narrative inquiry), and a follow-up discussion about the researchers' reconstruction of their story. Recruitment will take place through services in Nottingham and Liverpool. This study will help us understand how patients relate to, and make sense of, ECT and TMS, which contextual factors shape their experiences, and how these treatments fit into broader recovery journeys. The findings will inform development of patient-centred services, support shared decision-making, and promote a compassionate understanding of treatment experiences among healthcare professionals.

Interventions

OTHERThere is no intervention in this observation study (qualitative interviews about past treatment experiences)

There is no intervention in this observation study (qualitative interviews about past treatment experiences)

Sponsors

University of Nottingham
Lead SponsorOTHER
Mersey Care NHS Trust
CollaboratorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years or older * Previously received at least one TMS and one ECT session as treatment for major depression * Conversational in the English language * Capacity to give informed consent to take part in this study * Feels fully informed and well enough to be able to share potentially distressing past experiences

Exclusion criteria

* Participants may be excluded at the judgement of the PI if it is felt that the participant is at high risk of significant emotional distress from taking part in the interviews at this time

Design outcomes

Primary

MeasureTime frame
Co-created narratives and associated themesFrom enrollment to the completion of the follow-up feedback sesson

Countries

United Kingdom

Contacts

CONTACTSarah Research Assistant (Nottingham)
sarah.ottahal@nottingham.ac.uk+44
CONTACTPeggy Research Assistant (Liverpool)
yue.peng@merseycare.nhs.uk+44
PRINCIPAL_INVESTIGATORPaul M Briley

University of Nottingham

PRINCIPAL_INVESTIGATORJade Thai

Mersey Care NHS Foundation Trust

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 9, 2026