Periodontal Bone Loss, Periodontal Disease
Conditions
Keywords
Periodontitis, Laser, Open Flap, Minimally invasive, Coagulation, decontamination
Brief summary
The study involves the surgical treatment of patients with Stage I to III of periodontitis. Following completion of Steps 1 and 2 of periodontal therapy according to the EFP guidelines for the treatment of periodontitis, sites presenting with residual probing depths greater than 5 mm and non-contained periodontal defects will undergo open-flap debridement and decontamination. In one group, debridement and decontamination will be performed using manual and ultrasonic instrumentation, whereas in the other group, the same treatment will be supplemented with laser therapy.
Interventions
PROCEDUREMechanical Open Flap debridement
Open-flap debridement will be performed under local anesthesia. Following incisions, a full-thickness mucoperiosteal flap will be elevated to provide adequate access to the periodontal defect and root surfaces. Granulation tissue will be carefully removed, and thorough root surface debridement will be performed using manual and ultrasonic devices. After instrumentation surgical site, the flap will be repositioned and stabilized with sutures to achieve appropriate wound closure.
PROCEDURELaser assisted open flap debridement
Open-flap debridement will be performed under local anesthesia. Following intrasulcular incisions, a full-thickness mucoperiosteal flap will be elevated to provide adequate access to the periodontal defect and root surfaces. Granulation tissue will be carefully removed, and thorough root surface debridement will be performed using manual and ultrasonic instrumentation. In the test group, laser irradiation will subsequently be performed within the periodontal pocket and on the exposed root surface as an adjunctive decontamination procedure. After instrumentation, laser treatment, and irrigation of the surgical site, the flap will be repositioned and stabilized with sutures to achieve appropriate wound closure.
Sponsors
University of Bari Aldo Moro
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Adults in good general health * Signed informed consent * Periodontal disease treated with non surgical step.
Exclusion criteria
* Systemic conditions affecting bone healing * Uncontrolled periodontal disease * Smoking \>10 cigarettes/day * Pregnancy or lactation * Use of medications interfering with bone metabolism
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Periodontal probing depth | 3 month | Will be measured with dental prob the probing depth before 3 month of the surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bleeding on probing | 3 month | The % os BoP will be value after 3 months. |
Countries
Italy
Contacts
CONTACTGiuseppe D'Albis, Dr.
CONTACTMattia Marra, Dr.
PRINCIPAL_INVESTIGATORGiuseppe D'Albis, Dr
University of Bari Aldo Moro
PRINCIPAL_INVESTIGATORMattia Marra, Dr
University of Bari Aldo Moro
STUDY_DIRECTORSaverio Capodiferro, Prof
University of Bari Aldo Moro
Outcome results
None listed