Postoperative Nausea and Vomiting (PONV)
Conditions
Keywords
Cardiac Surgery, Postoperative Pain, Preoperative Anxiety, Preoperative Depression, Multimodal Analgesia, Postoperative Nausea and Vomiting, Rescue Analgesia, Numeric Rating Scale
Brief summary
This observational study will evaluate factors that may be associated with pain during the first 24 hours after open heart surgery. The study will include adult patients who underwent coronary artery bypass grafting (CABG), heart valve surgery, or combined cardiac surgery. Researchers will retrospectively review existing medical records to examine whether patient characteristics, preoperative anxiety and depression, and factors related to surgery and anesthesia are associated with postoperative pain. The study will also evaluate postoperative nausea and vomiting and the need for additional pain medication. No treatment or intervention will be assigned to participants as part of this study. Study data will be collected retrospectively from existing medical records.
Detailed description
Postoperative pain after cardiac surgery is influenced by multiple patient-related, psychological, surgical, and perioperative factors. The relative contribution of these factors to early postoperative pain and related outcomes remains uncertain. This retrospective observational cohort study will evaluate factors associated with early postoperative pain in adult patients who underwent open cardiac surgery, including coronary artery bypass grafting, valve surgery, or combined cardiac procedures. Existing medical records will be retrospectively reviewed. The analysis will examine demographic characteristics, preoperative anxiety and depression, surgical characteristics, and perioperative factors in relation to early postoperative pain. Preoperative anxiety and depression will be evaluated using available Hospital Anxiety and Depression Scale (HADS) scores. Postoperative pain will be assessed using Numeric Rating Scale (NRS) measurements recorded during the first 24 hours after surgery. Postoperative nausea and vomiting and the requirement for additional rescue analgesia will also be evaluated as related postoperative outcomes. Associations between these clinical and psychological factors and postoperative outcomes will be examined using appropriate statistical analyses. No study-specific treatment or intervention will be assigned to participants, as all study data will be obtained retrospectively from existing medical records.
Interventions
None listed
Sponsors
Antalya Training and Research Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥18 years * Underwent open cardiac surgery, including coronary artery bypass grafting (CABG), valve surgery, or combined cardiac surgery * Complete perioperative and postoperative pain data available in the medical records
Exclusion criteria
* Incomplete medical records * Reoperation within the first 24 postoperative hours * Chronic opioid use * Cognitive impairment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean Postoperative Pain Score During the First 24 Hours | First 24 hours after surgery | Postoperative pain will be assessed at rest using the 0-10 Numeric Rating Scale (NRS), where 0 indicates no pain and 10 indicates the worst pain. NRS scores recorded at 0, 3, 6, 12, and 24 hours after the initial postoperative assessment in the intensive care unit will be used to calculate the mean pain score (NRSmean) for the first 24 postoperative hours. |
Countries
Turkey (Türkiye)
Contacts
CONTACTMeltem Ceylan Delice, MD
Outcome results
None listed