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Changes in the Angle of Uterine Flexion as the Bladder Fills

Prospective Study of the Changes in the Angle of Uterine Flexion as the Bladder Fills

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07803627
Acronym
FLEXIMIX3
Enrollment
30
Registered
2026-09-03
Start date
2026-09-15
Completion date
2027-03-15
Last updated
2026-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine Anteflexion

Keywords

Uterine anteflexion, Nulliparous women, Bladder filling, Ultrasound measurements

Brief summary

The goal of this clinical trial is to evaluate how bladder filling affects the uterine flexion angle in adult nulliparous women with a uterine flexion angle \<90° when the bladder is empty. The main questions it aims to answer are: How does the uterine flexion angle change as bladder volume increases? What bladder volume is needed to obtain a uterine flexion angle \>90°? Participants will: Drink 600 mL of water following a standardized protocol. Undergo repeated suprapubic ultrasound measurements of bladder volume and uterine flexion angle. Remain under observation until urination or for a maximum of 4 hours. No comparison group is included in this study.

Interventions

Repeated ultrasound measurements, alternating between volume and angle of flexion, immediately following a hydration protocol and then bladder emptying.

Sponsors

University Hospital, Brest
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Adult woman * Nulliparous * Registered with a social security scheme * Uterine flexion angle \< 90°, empty bladder

Exclusion criteria

* Pregnant woman * Woman wishing to become pregnant and currently trying to conceive * Primary amenorrhoea * Menopause * History of surgical termination of pregnancy * History of medical termination of pregnancy * History of hysterectomy * History of conisation * Absence of the uterus * Symptoms of urinary tract infection (gross haematuria, burning on urination, frequent urination) * Under legal guardianship (curatorship, trusteeship)

Design outcomes

Primary

MeasureTime frameDescription
Uterine Flexion Angle Measured at Different Bladder Volumes in Nulliparous Women With an Anteverted Uterus and Baseline Uterine Flexion Angle <90°4 hoursThe relationship between bladder volume and the angle of uterine flexion, as determined from repeated ultrasound measurements in the participants.

Countries

France

Contacts

CONTACTBenoit CHIRON, MD
benoitchiron@yahoo.fr02 98 40 19 21

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 4, 2026