Kidney Neoplasm, Renal Mass up to 7cm
Conditions
Keywords
Kidney Tumor, Partial Nephrectomy, Robotic Surgical Procedures, Minimally Invasive Surgical Procedures, Optical Imaging
Brief summary
The goal of this prospective observational study is to learn about the use of a novel imaging technique called hyperspectral imaging in adult participants who are having surgery for removing a tumor from their kidney. Hyperspectral imaging works by shining light on a structure (in this case, the kidney tissue with the tumor) and capturing how it reflects hundreds of very narrow color bands, including ones the human eye can't see. These patterns depend on the composition of the tissue and for example how well blood is flowing through the tissue. By studying these patterns, the investigators want to understand if this technique can be helpful for the surgery where only the part of the kidney with the tumor is removed. The main questions it aims to answer are: * Can hyperspectral imaging show the areas of blood flow in the kidney during surgery? * Is there a connection between the detected patterns of light and the type of kidney tumor? The imaging will happen during the already planned surgery and the participant does not need to undergo any additional tests.
Interventions
None listed
Sponsors
University of Leipzig
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with a kidney tumor ≤7cm * planned robot-assisted partial nephrectomy * age ≥ 18 years
Exclusion criteria
* patients with a previous surgery on the affected kidney * patients with a fully intrarenal/endophytic tumor without an exophytic component * previous malignancy with ongoing or planned nephrotoxic chemotherapy * current immunosuppression (e.g., organ transplantation, leukemia) * pregnancy, lactation, or women who wish to have children * inability to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation of hyperspectral imaging (HSI) data with clamping technique during robot-assisted partial nephrectomy (RAPN) | day of surgery |
| Correlation of HSI data with histopathological report | day of surgery |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of HSI data with demographic parameters | day of surgery |
| Correlation of HSI data and respective clamping technique with postoperative kidney function | from the day of surgery until discharge (up to 6 days) |
Countries
Germany
Contacts
CONTACTJens-Uwe Stolzenburg, Professor Dr.
CONTACTDoreen Trebst, Dr.
Outcome results
None listed