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Factors Affecting Postoperative Recovery From Common Bile Duct Cysts in Children: A Multicenter Retrospective Analysis Based on Perioperative Clinical Characteristics

Factors Affecting Postoperative Recovery From Common Bile Duct Cysts in Children: A Multicenter Retrospective Analysis Based on Perioperative Clinical Characteristics

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07800169
Enrollment
550
Registered
2026-09-02
Start date
2026-01-01
Completion date
2026-07-31
Last updated
2026-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Choledochal Cyst Resection

Keywords

choledochal cyst, postoperative flatus, Roux-en-Y hepaticojejunostomy, pediatric surgery

Brief summary

This retrospective study aims to systematically analyze the factors influencing short-term rehabilitation and liver function recovery after radical surgery for pediatric common bile duct cysts, identify independent risk factors, construct a risk prediction model, and provide an evidence-based basis for optimizing perioperative management.

Interventions

None listed

Sponsors

Wuhan Children's Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Weeks to 16 Years
Healthy volunteers
No

Inclusion criteria

1\) Age between 0-16 years, meeting the age-based classification criteria for pediatric patients; 2) Diagnosis of common bile duct cyst confirmed by imaging studies (liver and gallbladder ultrasonography, MRCP, or CT), with histological typing performed according to the Todani classification system; 3) First-time surgical resection of the common bile duct cyst combined with radical Roux-en-Y hepatojejunal anastomosis; 4) Complete clinical medical records, preoperative laboratory test data, intraoperative surgical documentation, postoperative rehabilitation and follow-up data; 5) The study cases are affiliated with respective participating research centers, and inpatient and follow-up data can be readily retrieved.

Exclusion criteria

1\) Children with severe end-stage liver cirrhosis, irreversible liver failure, or malignant biliary tract tumors; 2) Children with severe multi-organ failure (e.g., cardiac, pulmonary, or renal failure) who cannot be adequately assessed for surgical prognosis; 3) Children undergoing secondary surgery or those with recurrent choledochal cysts; 4) Children who have only undergone palliative stoma creation or percutaneous drainage without receiving radical surgical intervention; 5) Cases in which critical perioperative clinical data are missing, making it impossible to meet the requirements for data analysis.

Design outcomes

Primary

MeasureTime frame
First flatus time (hours)From the date of surgery until the date of first flatus, assessed up to 7 days postoperatively.
First defecation timeFrom the date of surgery until the date of first defecation, assessed up to 7 days postoperatively.
Postoperative length of hospital stay (days)From the date of surgery until the date of hospital discharge, assessed up to 3 months postoperatively.

Countries

China

Contacts

STUDY_CHAIRXueqiang Yan, Doctor

Wuhan Children's Hospital

PRINCIPAL_INVESTIGATORLiang Ge

Tianjin Children's Hospital

PRINCIPAL_INVESTIGATORChen Yu

Anhui Provincial Children's Hospital

PRINCIPAL_INVESTIGATORZhu Jin

Zunyi Medical College

PRINCIPAL_INVESTIGATORXiaoxia Wu

Shanxi Provincial Maternity and Children's Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 3, 2026