Dentine Autograft in Extraction Socket, Prf in Extraction Socket
Conditions
Brief summary
The present study will be performed to: evaluate alveolar bone healing using dentin autograft mixed with platelet-rich plasma in extraction socket vs graftless healing.
Detailed description
When teeth are extracted, a certain amount of bone loss or resorption occurs, usually about 30-60%. This loss is typically three-dimensional in nature, with width loss or horizontal deficiency developing to a greater extent than other types of deficiencies. An alveolar defect can be classified as the loss of labial or buccal cortical or medullary bone. In some cases, both exist. Although all alveolar defects present challenges when planning a dental implant procedure, if the defect is in the buccal cortex or cortical plate after tooth extraction, this can create significant difficulties in the reconstruction of a dental implant. Bone loss or bone augmentation techniques have been developed to counteract alveolar defects, such as guided bone regeneration, onlay block bone grafting, ridge/split bone grafting, and alveolar distraction osteogenesis. These procedures can help improve an alveolar defect and prepare the alveolar ridge for a successful dental implant.
Interventions
PROCEDUREDENTION AND PRF APPLICATION IN SOCKET
DENTION IS HARVESTED FROM NON RESTORABLE TOOTH TO BE GROUND AND MIXED WITH PRF TO BE APPLIED IN EXTRACTION SOCKETS \< 1ST GROUP\> PRF IS WITHDROWN FROM BLOOD AND CENTRIFUGED TO FORM A GRAFT TO BE APPLIED IN EXTRACTION SOCKETS \<2ND GROUP\> EXTRACTION SOCKETS ARE LEFT TO HEAL SPONTANUOUSLY
PROCEDUREPLATETELT RICH FIBRIN IN EXTRACTION SOCKET
DENTION IS HARVESTED FROM NON RESTORABLE TOOTH TO BE GROUND AND MIXED WITH PRF TO BE APPLIED IN EXTRACTION SOCKETS \< 1ST GROUP\> PRF IS WITHDROWN FROM BLOOD AND CENTRIFUGED TO FORM A GRAFT TO BE APPLIED IN EXTRACTION SOCKETS \<2ND GROUP\> EXTRACTION SOCKETS ARE LEFT TO HEAL SPONTANUOUSLY
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* 1\. Patients with hopeless non molar teeth that need extraction. 2. Age above 18 years. 3. Generally good state of health. 4. Agreement to participate in the study and also have to be able to attend postoperative clinical and radiological follow-up 6. Acquisition of informed consent.
Exclusion criteria
* 1- Patients refuse to be enrolled in this study 2- Patients with uncontrolled systemic disease. 3- Previously diagnosed hematological and neurological conditions.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Histomorphometric bone formation (%) | 3-6 months | a trephine bur is used to extract a sample from healed bone to be stained with H\&E and analyzed under microscope |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bone density (radiographic) Healing index | 3-6 months | type of bone is measerd on cbct scan after three months from healing of bone |
Countries
Egypt
Outcome results
None listed