Skip to content

Menthol Chewing Gum After Laparoscopic Colorectal Surgery

The Effect of Menthol Chewing Gum on Nausea and Vomiting, Bowel Function, and Recovery After Laparoscopic Colorectal Surgery: A Randomized Controlled Trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07796529
Enrollment
50
Registered
2026-09-01
Start date
2024-01-15
Completion date
2024-04-25
Last updated
2026-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel Functions, Postoperative Nausea and Vomiting, Postoperative Recovery

Keywords

Menthol Chewing Gum, Chewing Gum, Laparoscopic Colorectal Surgery, Postoperative Nausea and Vomiting, Bowel Function, Surgical Recovery, Nonpharmacological Intervention

Brief summary

This randomized controlled trial was conducted to evaluate the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery. A total of 50 patients were randomly assigned to an intervention group (n=25) or a control group (n=25). Participants in the intervention group received menthol chewing gum in addition to standard postoperative care, while participants in the control group received standard postoperative care only. Nausea, bowel function, and postoperative recovery were assessed during the first three postoperative days.

Detailed description

Postoperative nausea and vomiting and delayed return of bowel function are common concerns following laparoscopic colorectal surgery and may affect postoperative recovery. Chewing gum is a non-pharmacological intervention that may stimulate gastrointestinal activity. This randomized controlled trial evaluated the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery. Participants were randomly allocated to an intervention group or a control group. Both groups received routine postoperative treatment and nursing care. In the intervention group, participants chewed menthol gum for 30 minutes and repeated the intervention three hours later. The same procedure was applied on the first, second, and third postoperative days. Participants in the control group received routine postoperative treatment and care without menthol chewing gum. Postoperative nausea, bowel function, and recovery status were evaluated during the first three postoperative days. Postoperative recovery was assessed using the Surgical Recovery Status Scale, and nausea intensity was assessed using a Visual Analog Scale.

Interventions

Participants chewed menthol gum for 30 minutes, followed by a second 30-minute chewing session three hours later. This intervention was repeated on postoperative days 1, 2, and 3 in addition to standard postoperative care.

Sponsors

Sennur Kula Şahin
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Caregiver)

Intervention model description

Participants were randomly assigned in a 1:1 ratio to either the menthol chewing gum group or the standard care control group.

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Aged 18-60 years * Willing to participate in the study * At least literate * Able to communicate without cognitive, sensory, or verbal impairment * No diagnosed psychiatric disorder * No vertigo * Undergoing elective surgery * Not using sedative, anxiolytic, or similar medications * Able to speak Turkish * Able to chew gum * No allergy to menthol or mint * No history of jaw or oral surgery

Exclusion criteria

* Absence of teeth * Unwilling to chew gum

Design outcomes

Primary

MeasureTime frameDescription
Postoperative Nausea and Vomiting FrequencyPostoperative days 1, 2, and 3The frequency of postoperative nausea and vomiting was recorded for each participant during the first three postoperative days. Higher values indicate a greater frequency of nausea and vomiting.

Secondary

MeasureTime frameDescription
Postoperative Gas Passage FrequencyPostoperative days 1, 2, and 3The frequency of defecation was recorded during the first three postoperative days as an indicator of postoperative bowel function.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 2, 2026