Post-Extraction Wound Healing in Elderly

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07796269

Enrollment

Registered

2026-09-01

Start date

2026-11-01

Completion date

2030-11-01

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound Healing

Keywords

extraction, elderly

Brief summary

Patients presenting to the University of Nebraska Medical Center College of Dentistry for a posterior extraction will be offered participation in the study. Prior to extraction, subjects will undergo clinical measurements, xray, gingival crevicular fluid (GCF) and saliva sampling and a blood draw. Following atraumatic tooth extraction, the subjects will be reevaluated for healing at 1, 2-weeks and 3 months. At each appointment, GCF, saliva and wound fluid (WF) will be collected and at 3 months a second xray will be taken.

Interventions

PROCEDUREtooth extraction

posterior tooth extraction

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to 80 Years

Healthy volunteers

Inclusion criteria

* needs posterior tooth extracted * no systemic conditions or meds affecting wound healing * non-smoker

Exclusion criteria

* systemic conditions or meds known to affect wound healing * smokers

Design outcomes

Primary

Measure	Time frame	Description
Amount of Interleukin-1 beta (IL1-B) in gingival crevicular at baseline	Baseline	Measurement of IL1B in GCF

Secondary

Measure	Time frame	Description
Bone Density	3 months	Change in bone density post-extraction

Countries

United States

Contacts

CONTACTAmy Killeen, DDS, MS

akilleen@unmc.edu4024727848

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 15, 2026