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Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in in Women With Hypertensive Disorders of Pregnancy.

Comparison Between Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in Predicting of Adverse Perinatal Outcome in Women With Hypertensive Disorders of Pregnancy.

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07795320
Acronym
CPR_AUCR2026
Enrollment
130
Registered
2026-08-31
Start date
2026-11-01
Completion date
2028-04-01
Last updated
2026-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension Disorders in Pregnancy

Keywords

Hypertension With Pregnancy

Brief summary

The primary aim of this study is to evaluate the predictive value of the Amniotic-Umbilical-to-Cerebral Ratio (AUCR) in predicting composite adverse perinatal outcomes in women with hypertensive disorders of pregnancy and to compare its predictive performance with the traditional Cerebroplacental Ratio (CPR)

Detailed description

A prospective cohort study will be conducted to compare the predictive accuracy of the cerebroplacental ratio (CPR) and the amniotic-umbilical-to-cerebral ratio (AUCR) for composite adverse perinatal outcomes among women with hypertensive disorders of pregnancy.

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Women aged 18-40 years, inclusive. * Singleton viable pregnancy. * Gestational age ≥32 weeks. * Pregnancy complicated by a hypertensive disorder. * Women who provide written informed consent.

Exclusion criteria

* Multiple gestation. * Fetuses with known chromosomal or major congenital anomalies. * Maternal diseases likely to independently affect fetal circulation or perinatal outcome, such as significant cardiac disease or other major systemic diseases. * Inability to complete the required follow-up.

Design outcomes

Primary

MeasureTime frameDescription
number of cases with NICU admission6 weeksnumber of neonates admitted in neonatal care unit within 24 hours after delivery

Secondary

MeasureTime frameDescription
weight of birth1 daybirth weight in grams after delivery

Contacts

CONTACTAbdelrahman Mahmoud, MD
abdelrahman_mahmoud2@aun.edu.eg08802089519

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 1, 2026