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Antioxidant Nutrition and Facial Exercise for Skin Aging

Effects of a Combined Antioxidant Nutrition and Facial Exercise Program on Skin Quality and Wrinkle Severity in Middle-Aged Women

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07792447
Enrollment
120
Registered
2026-08-28
Start date
2026-08-25
Completion date
2026-11-25
Last updated
2026-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Facial Skin Aging and Wrinkle Severity

Keywords

Facial Exercise, Skin Aging, Facial Wrinkles, Middle-Aged Women

Brief summary

This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women. Participants will be randomly assigned to an intervention group or a control group. The intervention group will follow a structured antioxidant-rich dietary program combined with facial exercises, while the control group will maintain their usual lifestyle. Skin quality and wrinkle-related outcomes will be assessed at baseline and after the 12-week intervention using standardized objective measurements

Interventions

BEHAVIORALCombined Antioxidant Nutrition and Facial Exercise Program

Participants in the intervention group will complete a 12-week combined program consisting of an antioxidant-rich dietary intervention and structured facial exercises. The dietary component will emphasize regular consumption of antioxidant-rich foods, while the facial exercise component will target major facial muscle groups according to a standardized exercise protocol. Participants will be instructed to follow the program throughout the 12-week intervention period

Sponsors

University of Zakho
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
45 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

\- Inclusion Criteria: Female participants aged 45-50 years. Willing and able to participate in the 12-week intervention program. Willing to follow the assigned dietary and facial exercise program. Willing to maintain their usual skincare routine unless otherwise instructed by the study protocol. Able to provide informed consent.

Exclusion criteria

Current smoking. Facial aesthetic procedures such as botulinum toxin injections, dermal fillers, laser treatment, chemical peels, or similar procedures within the predefined period before enrollment. Current dermatological disease or skin condition that may affect facial skin measurements. Uncontrolled chronic medical conditions that may influence skin health or participation in the intervention. Planned initiation of new skincare treatments, cosmetic products, or aesthetic procedures during the 12-week study period. Inability to perform the facial exercise program safely or comply with the dietary intervention and study procedures

Design outcomes

Primary

MeasureTime frameDescription
Change in Mean Crow's Feet Wrinkle DepthBaseline to 12 weeksChange in the mean bilateral crow's feet wrinkle depth from baseline to week 12, assessed using standardized three-dimensional skin imaging. Measurements will be obtained from both sides of the face and averaged to provide the participant-level value. Lower post-intervention values indicate improvement in wrinkle depth

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 29, 2026