Postoperative Pain, Pulp Necrosis
Conditions
Keywords
Cocoa Husk, Calcium hydroxide, Intra-canal medication
Brief summary
The study will aim to evaluate the postoperative pain and bacterial load after application of two intracanal medications in mandibular first molar teeth with necrotic pulp. Methods (Participants, Interventions, and Outcomes) Study Setting: This randomized clinical trial will include 36 patients, equally allocated into three groups (12 patients each). Participants will be recruited from the Outpatient Clinic of the Endodontic Department, Faculty of Oral and Dental Medicine, Future University in Egypt. All treatments will be performed by a postgraduate master's degree candidate using a Ritter dental unit (Germany) and Sirona digital intraoral radiography (Nanopix, size 2). Eligibility Criteria: Eligible participants will be 18-40 years old with necrotic pulp and symptomatic apical periodontitis in restorable mandibular first molars (Type III mesial and distal canals) and willing to participate. Exclusion criteria include pregnancy, systemic diseases, recent use of analgesics or antibiotics, bruxism or clenching, severe traumatic malocclusion, and teeth with periapical radiolucency, root resorption, pulp stones/calcifications, or previous endodontic treatment.
Interventions
DRUGRoot canal treatment with intracanal medication by calcium hydroxide for one week.
Following cleaning and shaping of the root canal, calcium hydroxide paste will be used as an intracanal medicament for one week to reduce bacterial load before the final root canal
DRUGRoot canal treatment with intracanal medication by cocoa husk for one week
Root canal treatment with intracanal medication by cocoa husk for one week
DRUGRoot canal treatment with intracanal medication by calcium hydroxide with cocoa husk for one week.
Following cleaning and shaping, no intracanal medicament will be used. The root canal will be obturated according to the study protocol.
Sponsors
Future University in Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
1. Patients with an age range between 18 to 40. 2. Patients with necrotic pulp. 3. Restorable teeth. 4. Positive patient acceptance for participating in the study. 5. Type III distal and mesial canal of the first mandibular molar. 6. Patients have necrotic pulp with symptomatic apical periodontitis in mandibular first molars. \-
Exclusion criteria
1. Pregnant females 2. Medically compromised patients. 3. Patients having analgesics before the treatment 4. If antibiotics have been administered during the past two weeks pre-operatively. 5\. Patients having bruxism or clenching 6. Patients have severe malocclusion associated with traumatic occlusion. 7. Teeth that have: a. Peri-apical radiolucency b. Root resorption. c. Pulp stones or calcifications. d. Previous endodontic treatment \-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain | 6,12,24,48,and 72hours after root canal treatment by numerical rate scale (NRS) |
Secondary
| Measure | Time frame |
|---|---|
| bacterial load reduction | S1: after access cavity and before RCT. S2: after mechanical instrumentation S3: after intracanal medicament removal By Colony Forming Unit analysis18 CFU/ml (%) |
Countries
Egypt
Contacts
PRINCIPAL_INVESTIGATORfatouh
future university
Outcome results
None listed