Goal Directed Fluid Therapy in Craniotomy Operations Guided By Pulse Pressure Variability (PPV) Versus Central Venous Pressure (CVP)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07787455

Enrollment

Registered

2026-08-26

Start date

2026-01-11

Completion date

2026-08-01

Last updated

2026-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

VOLUME OF FLUID

Brief summary

the aim from the study is goal directed fluid therapy in carniotomy operations guided by ppv versus cvp

Detailed description

it is a study to compare the effectiveness of goal directed fluid therapy (GDTF) in patients undergoing craniotomy when gudied by cvp group (25 cases) versus group ppv (25 cases) .the primary outcome is the amout of fluid given to the patient gudied by cvp compared to amount given gudied by ppv . secondaary outcome include: incidence of hypotesion ,vasopressor use, serum lacatate ,pulmonary complications , PONV ,length of hospital stay

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Inclusion criteria

* ASA I,II AGE 18-65

Exclusion criteria

CHRONIC CARDIC ARRHYTHMIA FLASE HIGH CVP ALTERED MYOCARDIAL FUNCTION PERIPHRAL VASCULAR DISEASE SEVER RESPRITORY DISEASE PEREGANACY PATIENT REFUSAL EXCESSIVE BLOOD LOSS OPERATIONS \-

Design outcomes

Primary

Measure	Time frame	Description
TOTAL VOLUME OF FLUIDS	INTRAOPRETIVE TIME SNICE INDUCTION TILL END OF OPERATION	COMPARE INRAOPRETIVE CRYSTELLOIDS VOLUMES BETWEEN CVP GUDIED AND PPV GUDIED GROUP IN CRANIOTOMY OPERATIONS

Countries

Egypt

Outcome results