R-GASTIM- Study of Gastric Cancer Operable

R-GASTIM - Clinicobiological Cohort of Gastric Cancers

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07787052

Acronym

R-GASTIM

Enrollment

Registered

2026-08-26

Start date

2024-09-30

Completion date

2027-09-30

Last updated

2026-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancers

Keywords

gastric cancer, microenvironment, neoadjuvant chemotherapy

Brief summary

Clinicobiological cohort of gastric cancers operated in our institution.

Detailed description

Study of microenvironment of gastric cancers using tumor and lymph nodes, collected as per standard of care. Analysis by RNASeq and HyperIon

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients with histologically proven non-metastatic resectable gastric and gastroesophageal junction adenocarcinoma, Stage IB to III be treated with standard neoadjuvant chemotherapy * Knwon response to neoadjuvant chemotherapy as per TRG criteria * Surgery of primary tumor done at Centre Léon Bérard. Availability of archival FFPE tumor block from initial diagnosis with at least 20% of tumor cells and collected lymp nodes

Exclusion criteria

* Patient refusal to participate to this clinicobiological cohort

Design outcomes

Primary

Measure	Time frame	Description
Gene expression	surgery	Transcriptom of Surgery and lymp node specimen

Secondary

Measure	Time frame	Description
HyperIon	surgery	Hyperion data on surgery and lymph nodes sample

Countries

France

Contacts

CONTACTClelia Coutzac, MD,PhD

clelia.coutzac@lyon.unicancer.fr0033478782828

Outcome results