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Dialectic Behaviour Therapy (DBT) for People With Autism: A Multiple Baseline Single Case Design

Dialectic Behaviour Therapy (DBT) for People With Autism, Emotion Regulation Difficulties and Self-harm Behaviour: A Multiple Baseline Single Case Design

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07786883
Acronym
DGT-ASS
Enrollment
6
Registered
2026-08-26
Start date
2026-09-01
Completion date
2028-02-01
Last updated
2026-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Brief summary

The goal of this experimental study is to test the effectiveness of Dialectic Behavioural Therapy in patients with Autism Spectrum Disorder. The aim questions are: 1. What is the effect of DBT on maladaptive emotion regulation strategies and emotional well-being in patients with ASD? 2. Is the use of DBT skills associated with a reduction in maladaptive emotion regulation strategies and an increase of emotional well-being over time? 3. What are the dynamics over time between maladaptive emotion regulation strategies, emotional well-being and sensory overload? Participants will: * Follow DBT of 10 months * Keep a diary on their urge of maladaptive emotion regulation strategies and well-being

Interventions

BEHAVIORALDialectic Behavioural Therapy

Dialectic Behavioural Therapy for emotion regulation, adapted to individuals with Autism Spectrum Disorder

Sponsors

GGZ Friesland
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

This study will be a Single Case Experimental Design (SCED). Therefore each case functions as their own control. Daily diary data will be analysed, just like secondary questionnaire outcomes.

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* DSM-5 diagnosis of ASD * Sufficient understanding, as demonstrated in conversation with intake therapist; * Explicit behavioural problems, which, according to patient and therapist, lead to functional problems (like suicidal ideation, auto mutilation, emotional outburst and interpersonal conflicts); * BMI \> 17; * Commitment to the therapy and shared goals as assessed by intake therapist;

Exclusion criteria

* Antisocial behaviour which interrupts the group climate; * Presence of a trauma-related disorder that is likely to interfere with the ability to engage effectively in DBT or that requires specialized trauma-focused treatment prior to or alongside DBT as assessed by intake team; * Excessive dependency on substances for which no parallel appropriate policy can be made; * Diagnosis of psychotic disorder if not stable; * Diagnosed with bipolar disorder.

Design outcomes

Primary

MeasureTime frameDescription
Maladaptive Emotion Regulation Strategies (MERS) measured assessed by the DBT diary (Linehan, 2016)From enrollment to end of treatment at 10 monthsMERS is the average of the urge to six maladaptive emotion regulation strategies: 1. suicidal thoughts/behaviours 2. self-harm, 3. eating problems 4. substance abuse 5. anger outburst 6. other All emotion regulation strategies are measured on a scale from 0 - 100. MERS will be created by adding scores of the six strategies together and divide it by 6.
Emotional well-being as assessed by the DBT diary (Linehan, 2016)From enrollment to end of treatment at 10 monthsThe daily diary measures emotional suffering and happiness on a scale from 0 - 100. Emotional suffering is inverted, following the logic that higher emotional suffering means lower emotional well-being. The variable well-being is created by averaging the invert of emotional suffering and happiness.

Secondary

MeasureTime frameDescription
Social behaviourAt start of baseline (T1), at end of treatment phase at 10 months (T2)As measured by the Vragenlijst Inventarisatie van Sociaal gedrag bij Volwassenen (VIS-V) (Horwitz et al. 2013). The VIS-V is a 44-item questionnaire that assess social behaviour, with answers ranging from 0 (= not applicable) to 2 (=cleary applicable). Higher scores mean lower social behaviour.
Emotion regulationAt the start of the baseline phase (T1), at the end of the treatment phase at 10 months (T2)As measured with the Difficulties in Emotion Regulation Scale (DERS) (Gratz \& Roemer, 2004). The DERS is a 36-item questionnaire with 5-point Likert answers, ranging from "almost never" to "almost always".
Generic psychopathology and functioningAt the start of the baseline phase (T1), at the end of the treatment phase at 10 months (T2)As measured with the Outcome Questionnaire-45 (OQ-45) (De Jong et al., 2008). The OQ-45 is a 45-item questionnaire, with answers ranging from never (0) to almost always (4). Some items are mirrored.

Countries

Netherlands

Contacts

CONTACTEmma Smeenge
emma.smeenge@ggzfriesland.nl+31610779265

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 27, 2026