Deviated Septum, Opioid Free Anesthesia
Conditions
Brief summary
Prospactive observational Clinical study
Interventions
OTHEROFA
OFA
Sponsors
Democritus University of Thrace
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Inclusion Criteria: * Adult patients aged 18 years or older * American Society of Anesthesiologists (ASA) physical status I-III * Patients scheduled for elective septal surgery under general anesthesia * Ability to provide written informed consent * Ability to understand and use the Numeric Rating Scale (NRS) for postoperative pain assessment 2.
Exclusion criteria
* Patient refusal to participate * Known allergy or hypersensitivity to any of the study medications * Contraindication to general anesthesia * Pre-existing chronic opioid use or chronic pain requiring regular analgesic treatment * Significant psychiatric or neurological disease that could interfere with postoperative pain assessment * Inability to understand or reliably report pain using the Numeric Rating Scale * Pregnancy * Significant hepatic or renal dysfunction * Any medical condition considered by the investigators to make participation inappropriate or unsafe
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of Opioid-Free Versus Opioid-Based Anesthesia on Postoperative Pain and Recovery in Patients Undergoing Septal Surgery | 18 months | Primary Outcome Measure Outcome Measure Title: Postoperative pain intensity measured by the Numeric Rating Scale (NRS) at 15 minutes after surgery Description: Postoperative pain intensity will be assessed using the 11-point Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain). Pain scores will be recorded at 15 minutes after surgery and will be summarized for each treatment group using mean ± standard deviation or median and interquartile range, as appropriate. Time Frame: 15 minutes after surgery Secondary Outcome Measures Outcome Measure Title: Postoperative pain intensity measured by the Numeric Rating Scale (NRS) at 1 hour after surgery Description: Pain intensity will be assessed using the 11-point Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain). Scores will be summarized for each treatment group using mean ± standard deviation or median and interquartile range, as appropriate. Time Frame: 1 hour after surge |
Countries
Greece
Outcome results
None listed