Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension)

Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension) - Prospective Trial

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07785635

Enrollment

100

Registered

2026-08-25

Start date

2025-05-01

Completion date

2026-09-01

Last updated

2026-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-induction Hypotension

Keywords

General anaesthesia, Post-induction hypotension, Fasting, Decrease of blood pressure

Brief summary

This monocentre prospective trial aims to evaluate the relationship between fasting time and the occurence of PIH (post-induction hypotension).

Detailed description

A decrease in blood pressure (BP) after induction of general anesthesia (GA) is a common phenomenon. The etiology is multifactorial (vasodilatory and dále negative inotropic effects of anaesthetics, reduction in sympathetic tone, the effect of positive pressure ventilation and others). Relative hypovolemia due to patient fasting is one of the factors that can have a significant influence on the decrease in blood pressure after induction of GA. Different lengths of fasting may thus lead to variations in both the incidence of hypotension after induction of GA (post-induction hypotension - PIH) and the severity of the BP drop.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Age ≥ 18 years * Patients undergoing planned surgical or diagnostic procedure * Intubation under general anaesthesia

Exclusion criteria

* Pregnancy * Disagreement with participation in the study * Bowel preparation

Design outcomes

Primary

Measure	Time frame	Description
Post induction hypotension (PIH)	1 month	The incidence of the post induction hypotension (PIH) will be assessed in the study subjects.
Seriousness of post induction hypotension (PIH)	1 month	Seriousness of post induction hypotension (PIH) will be assessed to determine whether patients with longer fasting time experience a significant reduction of blood pressure after induction of general anaesthesia.
Comparison of other PIH risk factors	1 month	The risk factors such as comordibity, chronic medication, type and doses of induction drugs will be compared.

Countries

Czechia

Contacts

CONTACTJiří Hynčica

jiri.hyncica@fno.cz0042059737

PRINCIPAL_INVESTIGATOROndřej Jor, MD, PhD, MBA

University Hospital Ostrava

Outcome results