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Tourniquet Pain Prevention During Distal Upper Limb Surgery

Brachial Plexus With Intercostobrachial Nerve or Serratus Anterior Plane Block for Tourniquet Pain Prevention During Distal Upper-Limb Surgery

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07784426
Enrollment
90
Registered
2026-08-25
Start date
2026-09-01
Completion date
2027-03-01
Last updated
2026-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia

Brief summary

Post-tourniquet pain remains a common problem. It disturbs the quality of anesthesia during brachial plexus block for distal upper-limb surgery. Current evidence shows that adding an intercostobrachial nerve block using the landmark-based technique can improve analgesia for medial upper-arm procedures.

Detailed description

Post-tourniquet pain remains a common problem. It disturbs the quality of anesthesia during brachial plexus block for distal upper-limb surgery. Current evidence shows that adding an intercostobrachial nerve block using the landmark-based technique can improve analgesia for medial upper-arm procedures. The serratus anterior plane block has also been proposed as an adjunct that may cover the intercostobrachial nerve territory. However, the landmark intercostobrachial nerve technique relies on a blind injection and may give inconsistent results. Moreover, high-quality head-to-head data comparing ultrasound-guided intercostobrachial nerve block with serratus anterior plane block for tourniquet pain prevention are lacking.

Interventions

PROCEDURESelective ultrasound guided Intercostobrachial nerve block

The patient will be positioned supine with the ipsilateral arm abducted. The ultrasound transducer will be positioned in the axilla along the mid-axillary line to visualize the thoracodorsal artery and vein and the fascia between the latissimus dorsi and serratus anterior muscles. The Intercostobrachial nerve often appears as a small hyperechoic structure lateral to the thoracodorsal vessels.

PROCEDURESerratus anterior plane block

The ultrasound transducer will be placed at the mid-axillary line at the level of the fourth or fifth rib to identify and inject a local anaesthetic drug in the plane between the latissimus dorsi and serratus anterior muscles.

Sponsors

Zagazig University
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
21 Years to 64 Years
Healthy volunteers
No

Inclusion criteria

* Elective unilateral distal upper-limb surgery (hand, wrist or forearm) with use of pneumatic upper-arm tourniquets under ultrasound-guided brachial plexus block.

Exclusion criteria

* Coagulopathy or therapeutic anticoagulation. * Local infection at injection sites. * Chronic opioid dependence.

Design outcomes

Primary

MeasureTime frameDescription
Tourniquet pain degreeThe first 60 minutes of tourniquet inflation.The visual analogue score of tourniquet pain at the end of first 60 minutes of tourniquet inflation with score 10 indicates worst pain and score 0 indicates no pain.

Secondary

MeasureTime frameDescription
Duration of tourniquet application.The first 2 hours intraoperative.The time from tourniquet inflation to tourniquet deflation.

Contacts

CONTACTMohamed Mohamed, MD
mgmelsayed@medicine.zu.edu.eg203350873
CONTACTAhmed Mohamed Hassan
11 13930038
STUDY_DIRECTORAmal Abdelazim Salah, MD

Department of Anesthesia, Intensive Care & Pain Management, Zagazig University

STUDY_CHAIROsama Abo Elfotouh Ismael Hassan, MD

Department of Anesthesia, Intensive Care & Pain Management, Zagazig University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 28, 2026