Inflammation, Autoimmunity and Healthy Ageing in Menopause Transition. An Observational, Cross-sectional Study

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07784400

Enrollment

300

Registered

2026-08-25

Start date

2026-09-01

Completion date

2028-09-01

Last updated

2026-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autoimmune Diseases, Menopause

Brief summary

The goal of this observational study is to investigate the prevalence of autoimmune or immune-mediated conditions in women during the menopausal transition (aged 40-60 years). The main questions it aims to answer are: * What is the prevalence of autoimmune or immune-mediated conditions in women aged 40-60 years across different reproductive stages? * How do inflammatory markers, resilience, lifestyle factors, and allostatic load scores relate to menopause-related symptoms and general health? Participants will complete evaluations, provide samples for clinical, immunological, and biochemical markers, and undergo assessments to analyze symptom burden and psychosocial determinants during the menopausal transition.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

40 Years to 60 Years

Inclusion criteria

* women aged 40-60 years referred to the menopause and gastroenterological outpatient clinic

Exclusion criteria

* inability to give consent

Design outcomes

Primary

Measure	Time frame
Prevalence of autoimmune or immune-mediated conditions during the menopausal transition	At the baseline visit (cross-sectional assessment)

Countries

Italy

Outcome results