Immediate Implant Placement in Chronic Infected Socket
Conditions
Keywords
Immediate dental implant, Infected Socket, Bone preservation,, Xenograft,, Vancomycin., Local delivery antibiotic
Brief summary
Adding local vancomycin to xenografts greatly benefits stability, bone density, and limits marginal bone loss in dental implants in infected socket.
Detailed description
Aim: to evaluate how adding vancomycin to the xenograft in the infected socket affects bone preservation during immediate implant placement. Background: Proper dental implant placement is crucial for successful osseointegration, as the resultant tiny gaps between the implant and bone can affect implant stability. These gaps are better filled with xenografts, which are easy to handle, widely available, and provide an osteoconductive framework that supports better implant outcomes. It's also important to prevent nearby infections, since the infected socket can damage both soft and hard tissues, raising the risk of peri-implantitis and further implant failure. Applying locally delivered antibiotics during placement can help protect and manage against early infections. Patients and methods: Twenty patients with mandibular extraction sockets participated in the study divided into two groups: 10 patients received a xenograft mixed with vancomycin (Group I), and 10 patients received a xenograft alone (Group II). Implant stability was assessed clinically at baseline and at 6 months only, while CBCT scans were used to monitor crestal bone loss and bone density at baseline, 6 months, and 9 months. Post-surgical complications were also monitored throughout the study period.
Interventions
PROCEDUREimmediate dental implants Placement in Chronic Infected Socket
(Clinical and Radiographic Study)
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
Clinical and Radiographic Study
Eligibility
Sex/Gender
ALL
Age
30 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* a badly decayed, hopeless tooth with periapical infection indicated for extraction and seeking implant placement
Exclusion criteria
* Acute infected socket. * Any socket with more than four wall defects.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| implant stability | baseline, 1, 6 months after implant placement | Changes in ISQ utilizing the Ostell ™ system |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| bone marginal level | baseline, 1, 6 and 9 months after treatment | Radiographic evaluation: Marginal bone height at the mesial and distal surfaces was measured in the panoramic view of the CBCT software, while the buccal and palatal surfaces were assessed in the cross-sectional view. |
| measure bone density | baseline, 1, 6 and 9 months after treatment | Radiographic evaluation,using CBCT software, the average density of the marginal and crestal bone around the implant was measured |
Countries
Egypt
Outcome results
None listed