Kidney Calculi
Conditions
Keywords
Pediatric Urolithiasis, Renal Stones, Large Renal Stones, Flexible Ureteroscopy, Flexible Ureterorenoscopy, Single-Use Flexible Ureteroscope, Laser Lithotripsy, Holmium:YAG Laser
Brief summary
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients. All enrolled participants underwent flexible ureteroscopic stone disintegration using a single-use flexible ureteroscope and Holmium laser lithotripsy. The study was designed to assess whether this minimally invasive approach could provide effective stone clearance with acceptable perioperative safety in children with large renal stones.
Interventions
PROCEDUREFlexible Ureteroscopic Stone Disintegration
Flexible ureteroscopy was performed using a 7.5-Fr single-use flexible ureteroscope. Renal stones were fragmented with a Holmium:YAG laser. A ureteral access sheath was used when feasible, and a double-J ureteral stent was placed at the end of the procedure.
Sponsors
Cairo University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Masking description
No masking was used because all participants received the same surgical intervention.
Intervention model description
All enrolled pediatric patients with large renal stones underwent flexible ureteroscopic stone disintegration using a single-use flexible ureteroscope and Holmium:YAG laser.
Eligibility
Sex/Gender
ALL
Age
0 Years to 13 Years
Healthy volunteers
No
Inclusion criteria
* Pediatric patients diagnosed with renal stones. * Renal stone size ≥2 cm. * Age younger than 14 years.
Exclusion criteria
* Uncontrolled urinary tract infection. * Impaired renal function. * Abnormal anatomical location of the kidney. * Congenital renal or ureteric anomalies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stone-Free Rate After Flexible Ureteroscopic Stone Disintegration | 1 month after the procedure | Stone-free status was assessed by computed tomography of the urinary tract (CTUT) after flexible ureteroscopic stone disintegration. The proportion of participants meeting the study-defined criteria for stone-free status was recorded. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Operative Time | Intraoperatively | Duration of the flexible ureteroscopic procedure was recorded for each participant. |
Countries
Egypt
Outcome results
None listed