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Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study

Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study. To Compare the Radiological, Clinical and Functional Outcomes of Short-segment Versus Long-segment Transpediclular Screw Fixation in Patients With Thoracolumbar Fractures AO-type B.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07777653
Enrollment
60
Registered
2026-08-20
Start date
2026-09-01
Completion date
2028-10-01
Last updated
2026-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracolumbar Compression Fractures

Brief summary

To compare the radiological, clinical and functional outcomes of short-segment versus long-segment transpediclular screw fixation in patients with thoracolumbar fractures AO-type B.

Detailed description

Thoracolumbar fractures represent the most common spinal injuries, predominantly occurring at the T11-L2 junction due to the biomechanical transition from the rigid thoracic to the mobile lumbar spine. This region accounts for approximately half of all traumatic spinal fractures, owing to changes in spinal curvature, facet joint orientation, and load-bearing mechanics (1). Surgical management aims to restore spinal stability, correct kyphotic deformity, decompress neural elements, and enable early mobilization. Two posterior fixation strategies exist: short-segment fixation (SSF), spanning one level above and below the fracture with one or 2 intermediate screws in the fractured vertebra itself, and long-segment fixation (LSF), spanning two or more levels above and below with one or 2 intermediate screws in the fractured vertebra itself. Short-segment constructs preserve more motion segments with reduced surgical morbidity, while long-segment constructs provide potentially greater stability (2). The optimal choice remains debated. A 2025 meta-analysis of 17 trials (1,031 patients) showed that LSF was associated with higher blood loss and longer operative time but better kyphosis correction maintenance and pain improvement (3). Short-segment fixation with intermediate screws at the fracture level has shown comparable results to LSF while preserving motion segments and reducing costs (4). There is no randomized trial on AO-type B. Given these controversies, a prospective comparative study in our population is warranted.

Interventions

PROCEDUREShort Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study

Thoracolumbar fractures represent the most common spinal injuries, predominantly occurring at the T11-L2 junction due to the biomechanical transition from the rigid thoracic to the mobile lumbar spine. This region accounts for approximately half of all traumatic spinal fractures, owing to changes in spinal curvature, facet joint orientation, and load-bearing mechanics (1). Surgical management aims to restore spinal stability, correct kyphotic deformity, decompress neural elements, and enable early mobilization. Two posterior fixation strategies exist: short-segment fixation (SSF), spanning one level above and below the fracture with one or 2 intermediate screws in the fractured vertebra itself, and long-segment fixation (LSF), spanning two or more levels above and below with one or 2 intermediate screws in the fractured vertebra itself. Short-segment constructs preserve more motion segments with reduced surgical morbidity, while long-segment constructs provide potentially greater stabi

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Age 18-65 years * Acute traumatic thoracolumbar fracture (AO type B) * Single-level fracture * Neurologically intact patient (ASIA E)

Exclusion criteria

* Pathological fractures (malignancy, infection, metabolic bone disease) * Significant neurological deficit (ASIA A-D) * Previous spinal surgery at or adjacent to the fracture level * 2 or more level fractures * Associated anterior column reconstruction requirement (corpectomy) * Polytrauma precluding early spinal surgery * Pregnancy * Performance of surgical decompression

Design outcomes

Primary

MeasureTime frameDescription
• Maintenance of correctionbaseline• Maintenance of correction (change in cobb angle from immediate postoperative to final follow-up at 12 months)

Secondary

MeasureTime frameDescription
Operative kyphosis correctionBaselineOperative kyphosis correction (change in cobb angle from preoperative to immediate postoperative)
• Anterior vertebral body height ratio restorationfrom pre operative to last follow up at 12 months
VASpre operative, post operative, at 3, 6 and 12 months follow-upVAS pain scores at all time points
ODIpre operative, post operative and at 3, 6 and 12 months follow upODI functional outcome scores at all time points

Countries

Egypt

Contacts

CONTACTAhmed Fawzy Ahmed Nafady, master
ahmed.17289890@med.aun.edu.eg+201092142188

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 21, 2026