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Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy Controls

A Multidimensional Physical Profile of Cervicogenic Headache: A Cross-Sectional Comparison With Nonspecific Neck Pain and Healthy Controls

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07776275
Enrollment
135
Registered
2026-08-20
Start date
2026-04-21
Completion date
2026-10-01
Last updated
2026-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervicogenic Headache, Chronic Neck Pain

Keywords

physical profile, myotonometry, upper trapezius, muscle stiffness, logarithmic decrement, pressure pain threshold, handgrip strength, craniovertebral angle, tragus to wall distance, cross-sectional study

Brief summary

The goal of this observational study is to compare physical findings across three adult groups. Cervicogenic headache (CGH) is a headache linked to a problem in the neck. Neck pain may affect posture, muscle function, grip strength, and sensitivity to pressure. Researchers do not know whether CGH has a distinct pattern of these findings. The main questions are: * Do posture, grip strength, muscle stiffness, elasticity, and pressure sensitivity differ among the groups? * Are any differences more closely associated with CGH than with neck pain? Researchers will compare adults ages 25 through 60. One group will include people with CGH lasting at least three months. Another group will include people with neck pain lasting at least six months. People in the neck pain group will have no headaches. Healthy participants will have no neck pain or headaches. Researchers will not provide treatment or change participants' usual care. Each participant will complete one study visit lasting about 15 minutes. Participants will: * Answer short questions about their health and pain * Stand while researchers measure their head and neck posture * Squeeze a device that measures grip strength * Complete brief tests of neck muscle stiffness and elasticity * Tell researchers when applied pressure first becomes painful Researchers will compare results across the three groups. The findings may guide future CGH assessment and treatment research.

Interventions

None listed

Sponsors

Istanbul Medipol University Hospital
Lead SponsorOTHER
Istanbul Kent University
CollaboratorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
25 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Inclusion Criteria: * Aged 25 to 60 years * Able to provide written informed consent * Meeting the criteria for one of the following groups: * Cervicogenic headache: physician diagnosis according to the International Classification of Headache Disorders, 3rd edition, with symptoms lasting at least 3 months * Chronic nonspecific neck pain: neck pain lasting at least 6 months without headache * Healthy control: no neck pain or headache

Exclusion criteria

* Receipt of physiotherapy for headache or neck pain during the previous 6 months * Diagnosis of a headache disorder other than cervicogenic headache, including migraine or tension-type headache, or a diagnosis of trigeminal neuralgia * History of cervical spine surgery or significant cervical trauma * Current or previous diagnosis of a tumor or cancer * Serious cardiovascular, cerebrovascular, hematological, metabolic, neurological, or psychiatric disorder * Rheumatoid arthritis * Congenital cervical abnormality * Cervical spondylolisthesis or cervical instability * Active infection * Temporomandibular joint dysfunction * Dizziness or visual disturbance accompanying headache * Any clinical red flag suggesting serious cervical pathology * Pregnancy or breastfeeding * Upper-extremity injury, surgery, or another condition affecting handgrip strength * Serious musculoskeletal disorder affecting cervical posture or muscle measurements * Inability to complete the questionnaire-based or instrument-based assessments

Design outcomes

Primary

MeasureTime frameDescription
Bilateral Upper Trapezius Muscle StiffnessDuring the single assessment session at enrollmentUpper trapezius muscle stiffness will be assessed bilaterally using the MyotonPRO device. Three consecutive measurements will be obtained at the midpoint between the C7 spinous process and the lateral border of the acromion. The mean of the three measurements will be used. Stiffness will be expressed in newtons per meter (N/m), with higher values indicating greater stiffness.
Bilateral Upper Trapezius Logarithmic DecrementDuring the single assessment session at enrollmentUpper trapezius logarithmic decrement will be assessed bilaterally using the MyotonPRO device at the same standardized measurement site. Three consecutive measurements will be obtained on each side, and their mean will be used. Logarithmic decrement is a dimensionless inverse indicator of tissue elasticity, with lower values indicating greater elasticity.

Secondary

MeasureTime frameDescription
Bilateral Handgrip StrengthDuring the single assessment session at enrollmentBilateral handgrip strength will be measured using a Jamar Hydraulic Hand Dynamometer set to the second handle position. Participants will perform three maximal contractions with each hand in a standardized seated position. The highest value for each hand will be recorded in kilograms, with higher values indicating greater handgrip strength.
Bilateral Upper Trapezius Pressure Pain ThresholdDuring the single assessment session at enrollmentPressure pain threshold will be measured bilaterally over the upper trapezius using a handheld pressure algometer with a 1-cm² probe. The measurement site will be the midpoint between the C7 spinous process and the lateral border of the acromion. Pressure will gradually increase until the participant first reports pain. Values will be recorded in kg/cm², with higher values indicating a higher pressure pain threshold.
Bilateral Suboccipital Pressure Pain ThresholdDuring the single assessment session at enrollmentPressure pain threshold will be measured bilaterally over the suboccipital region using a handheld pressure algometer with a 1-cm² probe. The measurement site will be located 2 cm lateral to the C2 spinous process. Pressure will gradually increase until the participant first reports pain. Values will be recorded in kg/cm², with higher values indicating a higher pressure pain threshold.
Tragus-to-Wall DistanceDuring the single assessment session at enrollmentTragus-to-wall distance will be measured in millimeters using a tape measure. Participants will stand with their heels, sacrum, and thoracic spine resting comfortably against a wall while maintaining a natural head position. The distance between the wall and the tragus will be recorded. Greater distances indicate greater forward positioning of the head.
Craniovertebral AngleDuring the single assessment session at enrollmentThe craniovertebral angle will be measured in degrees using a universal goniometer. The fulcrum will be positioned over the lateral projection of the C7 spinous process. The stationary arm will remain parallel to the floor, and the movable arm will point toward the tragus. Three measurements will be obtained, and their mean will be used. Smaller angles indicate greater forward head posture.

Countries

Turkey (Türkiye)

Contacts

CONTACTFatih Bali, PhD.
fatihbali@hotmail.com+905323937689

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 22, 2026