Acute Flaccid Paralysis, AFP, Gullian Barre Syndrome, Transverse Myelitis
Conditions
Keywords
acute flaccid paralysis, afp, Transverse myelitis, Gullian Barre Syndrome
Brief summary
This study is observational study aims to study the Clinical profile, Possible risk factors and Outcome of Acute flaccid paralysis in children at Sohag University Hospital. This study will include all children admitted to pediatric emergency and intensive care units with claim or suspicion to have acute falccid paralysis
Detailed description
This study is a single center, Observational Cross Sectional Hospital Based study aims to study the Clinical profile, Possible risk factors and Outcome of Acute flaccid paralysis in children aged from birth to 18 years old at Sohag University Hospital. All included children with acute flaccid paralysis will be subjected to: All routine investigation (complete blood count, C.R.P, blood gases, serum electrolytes, coagulation profile, liver and kidney function test) Imaging when indicated (Brain C.T, Brain and spine MRI, Nerve Conduction Study)
Interventions
No expiremental intervention. Data will be collected from routine cinical care, medical records and folow up visits according to standard hospital protocols
Sponsors
Study design
Eligibility
Inclusion criteria
* All patients admitted to pediatric emergency and intensive care units with claim or suspected to have acute flaccid paralysis aged from 1 month Up to 16 years old
Exclusion criteria
* Children with flaccid paralysis due to causes other than neurogenic causes. No clear history or clinical picture of definite neurological cause. incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Full recovery | 1 Year | Full restoration of muscle strength and function. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Partial Recovery with Residual Weakness | 1 Year | Persistent muscle weakness despite improvement |
| Permanent Paralysis | 1 Year | Irreversible loss of motor function due to destruction of motor neurons or severe nerve injury |
Countries
Egypt