Osteoarthritis (OA) of the Knee
Conditions
Keywords
Kinesio Taping, Platelet-Rich Plasma, Sham Taping, Knee Pain, Physical Function
Brief summary
This randomized controlled study evaluated whether kinesio taping provided additional benefits compared with sham taping in women with knee osteoarthritis who had received platelet-rich plasma (PRP) treatment as part of routine clinical care. Sixty women aged 50 to 65 years with Kellgren-Lawrence grade 1 to 3 knee osteoarthritis were randomly assigned in a 1:1 ratio to either kinesio taping or sham taping. Taping was applied once weekly for 6 weeks. Participants were assessed before taping and at weeks 3, 6, and 12. Outcomes included pain, function, physical performance, knee extensor strength, knee range of motion, and quality of life. The study aimed to determine whether kinesio taping after PRP treatment was more effective than sham taping in improving pain, function, physical performance, knee extensor strength, knee range of motion and quality of life.
Interventions
OTHERKinesio Taping
Therapeutic kinesio taping was applied once weekly for 6 weeks. A Y-cut tape was applied over the quadriceps muscle with 20% to 25% tension. Two web-cut tapes were applied around the knee with 10% to 15% tension. Each application remained in place for 5 days.
OTHERSham Taping
Sham taping was applied once weekly for 6 weeks. Two strips of tape were placed transversely 10 cm and 20 cm above the superior border of the patella without tape tension or a specific kinesio taping technique. Each application remained in place for 5 days.
Sponsors
Agri Ibrahim Cecen University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
50 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Female participants aged 50 to 65 years * Diagnosis of unilateral or bilateral knee osteoarthritis according to the American College of Rheumatology criteria * Kellgren-Lawrence radiographic grade 1 to 3 knee osteoarthritis * Received three platelet-rich plasma injections at 3-week intervals as part of routine clinical care * Ability to walk without an assistive device * Body mass index below 35 kg/m² * Willingness to participate and provision of written informed consent
Exclusion criteria
* Knee surgery within the previous 6 months * Intra-articular injection other than platelet-rich plasma within the previous 3 months * Systemic inflammatory joint disease, including rheumatoid arthritis, ankylosing spondylitis, or gout * Known allergy or adverse skin reaction to kinesio tape * Skin condition preventing tape application, including skin sensitivity or an open wound * Neuromuscular disease causing lower-extremity muscle weakness * Perceptual or coordination impairment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Knee Pain Intensity | Baseline and Weeks 3, 6, and 12 | Knee pain was assessed using an 11-point Numerical Rating Scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain intensity. |
| Function ((Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)) | Baseline and Weeks 3, 6, and 12 | Knee pain, stiffness, and physical function were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The pain, stiffness, and physical function subscale scores range from 0 to 20, 0 to 8, and 0 to 68, respectively. The total score ranges from 0 to 96. Higher scores indicate worse pain, stiffness, and functional limitation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 40-Meter Fast-Paced Walk Test | Baseline and Weeks 3, 6, and 12 | Functional walking performance was assessed using the 40-Meter Fast-Paced Walk Test. The time required to complete a total distance of 40 meters was recorded in seconds. A shorter completion time indicates better walking performance. |
| 9-Step Stair Test | Baseline and Weeks 3, 6, and 12 | Stair performance was assessed by recording the time required to ascend and descend 9 steps as quickly and safely as possible without assistance. The completion time was recorded in seconds. A shorter time indicates better functional performance. |
| Knee Extensor Strength | Baseline and Weeks 3, 6, and 12 | Maximal isometric knee extensor muscle strength was measured using a hand-held dynamometer with the hip and knee positioned at 90 degrees of flexion. Three measurements were performed, and the mean value was recorded in kilograms. Higher values indicate greater muscle strength. |
| Knee Flexion Range of Motion | Baseline and Weeks 3, 6, and 12 | Active knee flexion range of motion was measured using a universal goniometer. Three measurements were performed, and the mean value was recorded in degrees. |
| Change in 36-Item Short Form Health Survey (SF-36) Domain Scores | Baseline and Weeks 3, 6, and 12 | Quality of life was assessed using the 36-Item Short Form Health Survey (SF-36). The instrument evaluates eight domains: physical functioning, physical role limitations, emotional role limitations, emotional well-being, social functioning, energy/fatigue, bodily pain, and general health. Each domain is scored from 0 to 100, with higher scores indicating better health-related quality of life. |
| Knee Extension Range of Motion | Baseline and Weeks 3, 6, and 12 | Active knee extension range of motion was measured using a universal goniometer. Three measurements were performed, and the mean value was recorded in degrees. |
| 30-Second Chair Stand Test | Baseline and Weeks 3, 6, and 12 | Functional performance was assessed using the 30-Second Chair Stand Test. The number of complete stands performed from a 44-cm-high chair within 30 seconds was recorded. A higher number of completed stands indicates better functional performance. |
Countries
Turkey (Türkiye)
Outcome results
None listed