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Digital Mental Health for Asian Americans

Anise Health: Digital Mental Health for Asian Americans

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07771322
Enrollment
80
Registered
2026-08-18
Start date
2026-07-20
Completion date
2027-04-30
Last updated
2026-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asian, Cultural Adaptation, Culturally Responsive Care, Digital Health Intervention, Mental Health, Mood Disorders, Psychotherapy

Keywords

mental health, Asian American, Digital Mental Health, Anise Health, Cultural Adaptation, Asian, Digital Health

Brief summary

Aim 1: Assess clinicians' receptiveness and potential use of Anise's online platform digital tools for managing sociocultural stressors and revise the tools for implementation. We will recruit 8 new clinicians (intervention group) who will receive training and provide feedback on the digital tools. Aim 2: Evaluate the initial efficacy of the online platform digital tools for managing the impact of sociocultural stressors with 64 Asian American clients. The intervention group clinicians (receiving training and using the digital tools) and newly recruited 8 clinicians (not receiving training and not using the digital tools) for the control group will work with 4 clients each. The clinical outcome data of the clients will be analyzed to examine differences in the client prognosis between the control and intervention group. A successful outcome of this project will be digital materials that effectively address the impact of sociocultural stressors for Asian Americans on Anise Health's digital health platform.

Detailed description

Unique sociocultural factors significantly impact the lived experiences and mental health of Asian Americans. Yet, these factors are often not considered or are overlooked in conventional evidence-based practices for psychotherapy. Ample research has found that these culture-specific stressors can give rise to psychopathology (e.g., depression, anxiety, trauma, problematic substance use) among Asian Americans. The current diagnosis-driven, Eurocentric models of psychotherapy often do not account for these sociocultural determinants of mental well-being and can lack cultural sensitivity, leading to unsuccessful psychotherapy outcomes and a high burden from persistent mental health issues among this population. To address this gap, Anise Health (Anise) has been pioneering the technology-enabled delivery of mental health care for Asian Americans. Anise develops clinical protocols that incorporate culture and intersectionality into evidence-based practices and technologies that enable the delivery of personalized treatments. Anise's online platform also includes tailored digital tools for clients and clinicians to leverage in treatment. To improve access to high-quality mental health care services for Asian Americans, we will leverage our expertise and preliminary data to expand our online digital library of materials and tools. Specifically, the overall objective of this proposal is to develop and refine Anise Health's digital tools and accompanying clinician training programs for addressing key sociocultural factors in mental health treatments and to determine the feasibility and acceptability of these online platform tools. Our preliminary data elucidated common themes related to the negative impact of sociocultural stressors on clients' mental health outcomes, and the need for clinicians to address these issues in culturally-informed ways. Digital mental health clinical tools have been found to support treatment and homework adherence as they are easily accessible for clients and are easier for therapists to integrate into their treatment plans. However, existing digital mental health clinical tools were not developed for, nor tested with, the Asian American community and do not integrate their specific historical and sociocultural experiences. This project is a foundational step toward our long-term goal of demonstrating that Anise's online platform is effective in addressing unique sociocultural factors for Asian Americans.

Interventions

OTHERCulturally-attuned digital tools

The intervention includes clinicians receiving training to provide culturally-attuned mental health services to their clients through the use of digital tools. The digital tools include (a) digital worksheets designed to guide clients to explore and address sociocultural stressors, and (b) podcasts that help inform empirical knowledge on these issues. Clinicians are provided training how how they can effectively employ these digital tools with their clients to enhance their work, particularly regarding presenting concerns related to sociocultural stressors.

Sponsors

University of California, Berkeley
Lead SponsorOTHER
National Institute of Mental Health (NIMH)
CollaboratorNIH
Anise Health, Inc.
CollaboratorUNKNOWN

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Intervention model description

We will test whether there are significant differences in clients' outcomes related to presenting concerns between the intervention group (the 8 clinicians who were recruited and trained to use the digital tools) and the control group (another 8 clinicians recruited to work with clients without training and use of the digital tools). Both groups (control and intervention) will work with their clients as they normally would, with the difference being that the intervention group will be using the digital tools.

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

Clinician eligibility Inclusion Criteria: * New clinicians who have never provided services on the Anise Health platform

Exclusion criteria

* Existing clinicians on the Anise Health platform Client eligibility Inclusion Criteria: 1. Asian American adults (age 18-90 years) who seek mental health services 2. resides in states in which Anise Health clinicians are licensed to provide care, 3. has access to reliable internet connection, 4. has signed the Informed Consent form prior to participants' entry into the study.

Design outcomes

Primary

MeasureTime frameDescription
Frost Multidimensional Perfectionism Scale - Briefchange from baseline (assessed at baseline and at the end of 12-week period)Frost Multidimensional Perfectionism Scale - Brief (FMPS-Brief), an 8-item self-report measure assessing perfectionism across two subscales (evaluative concerns and striving). Total scores range from 8 (minimum) to 40 (maximum), with higher scores indicating greater perfectionism (worse outcome).
The System Usability ScaleAt the end of 12-week study periodSystem Usability Scale (SUS), a 10-item self-report measure assessing clinicians' perceived usability and acceptability of the digital tools. Total scores range from 0 (minimum) to 100 (maximum), with higher scores indicating better usability (better outcome).
Acculturative Stress Scalechange from baseline (assessed at baseline and at the end of 12-week period)Acculturative Stress Scale is a self-report measure that assesses stress experienced by immigrants and minorities due to cultural, social, and environmental adjustments. It is a 10-item self-report measure with total scores ranging from 10 (minimum) to 50 (maximum), with higher scores indicating greater acculturative stress (worse outcome).
The Multigroup Ethnic Identity Measure - RevisedChange from baseline (assessed at baseline and at the end of the 12 week period)Multigroup Ethnic Identity Measure - Revised (MEIM-R), a 6-item self-report measure assessing exploration of and commitment to one's ethnic identity. Scores are the mean of all items and range from 1 (minimum) to 5 (maximum), with higher scores indicating stronger ethnic identity.
Patient Health Questionnaire-9Change from baseline (assessed at baseline, mid point, and the end of the 12 week period)Patient Health Questionnaire-9 (PHQ-9), a 9-item self-report measure assessing depressive symptom severity over the past two weeks. Total scores range from 0 (minimum) to 27 (maximum), with higher scores indicating greater depression severity (worse outcome).
Generalized Anxiety Disorder-7Change from baseline (assessed at baseline, mid point, and the end of the 12 week period)Generalized Anxiety Disorder-7 (GAD-7), a 7-item self-report measure assessing anxiety symptom severity over the past two weeks. Total scores range from 0 (minimum) to 21 (maximum), with higher scores indicating greater anxiety severity (worse outcome).

Countries

United States

Contacts

CONTACTAlice Zhang, MBA
alice@anisehealth.co424-209-2386
CONTACTBrian Keum, PhD
briankeum@berkeley.edu510-473-7404

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 19, 2026