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Ultrasound Biomicroscopic Assessment of Intraocular Lens Tilt and Decenteration After Phacoemulsification

Ultrasound Biomicroscopic Assessment of Intraocular Lens Tilt and Decenteration After Phacoemulsification

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07769944
Enrollment
100
Registered
2026-08-18
Start date
2025-10-01
Completion date
2026-10-01
Last updated
2026-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decenteration, Intraocular Lens, Phacoemulsification, Tilt, Ultrasound Biomicroscopy

Brief summary

This study aims to assess intraocular lens (IOL) tilt and decenteration by means of ultrasound biomicroscopy after phacoemulsification.

Detailed description

Ultrasound biomicroscopy (UBM) is a non-invasive technique that uses high-frequency ultrasound to image the anterior segment of the eye. It can help as a diagnostic procedure in eyelid and anterior segment (cornea, conjunctiva, sclera, iris, ciliary body) pathology. It is a vital tool in evaluating anterior segment cysts or tumors and their diagnosis, evolution, and treatment. IOL tilt and decentration could be secondary to various aetiologies. The extent and direction of preoperative crystalline lens tilt have been demonstrated to be strongly correlated with postoperative tilt. Asymmetrical IOL fixation (partly in bag and partly in sulcus) and capsular tear during capsulorrhexis were reported as some causative factors to IOL tilt and decentration.

Interventions

Scanning is conducted with the non-dilated eye in a central position and the patient in the supine position. A drop of a topical anesthetic agent (benoxinate hydrochloride) is applied to both eyes.

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 45 Years
Healthy volunteers
No

Inclusion criteria

* Both sexes. * Patients with senile cataract prepared for phacoemulsification and IOL implantation.

Exclusion criteria

* Age \<45 years. * Complicated ataract. * Coexisting ocular disorders (Glaucoma, Pseudoexfoliation Syndrome, Sublaxation, Chronic Iridocyclitis). * Previous ocular surgery. * Complicated phacoemulsification.

Design outcomes

Primary

MeasureTime frameDescription
Measurement of intraocular lens tiltSix months after surgeryMeasurement of intraocular lens (IOL) tilt. The intraocular lens (IOL) position was measured as the Anterior Chamber Depth (ACD), defined as the distance between the anterior border of the hyperreflective line marking the central posterior corneal surface and the anterior IOL optic surface at the centre of the pupillary space.

Secondary

MeasureTime frameDescription
Measurement of intraocular lens decenterationSix months after surgeryAnterior Chamber Depth (ACD) was determined from the central inner corneal surface, perpendicular to the corneal surface to the most anteriorly visible part of the intraocular lens (IOL). A line (line AB) was drawn between the two scleral spurs (SSs), as the base line of reference for IOL position. Two perpendicular lines were drawn from both optical endpoints of the IOL (C and D) to the base line with intersection points (E and F). IOL decentration was equal to half of the differences between distance AE and FB, i.e. IOL decentration = (\|AE-FB\|) / 2.

Countries

Egypt

Contacts

CONTACTMennatullah A Farrag, MBBCH
menaa.adel@med.sohag.edu.eg00201129595307

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 19, 2026