Multiple Sclerosis, Spinal Cord Injury/Disorder, Stroke, Traumatic Brain Injury
Conditions
Brief summary
The purpose of this research study is to evaluate the effectiveness of an exercise training intervention (24-36 sessions) to improve muscle strength and endurance in the lower limbs of individuals with paralysis. Specifically, surface electrical stimulation or previously implanted stimulator will be used to stimulate the muscles during various forms of exercise training with the primary focus on improving overall endurance and maximal power output. For this study, peripheral stimulating electrodes will send electrical signals to the muscles enabling the production of coordinated movements for exercise such as cycling or rowing.
Interventions
OTHERExercise with Electrical Stimulation
Neuromuscular electrical stimulation for paralyzed muscles to complete exercise (cycle ergometer, hybrid arm leg cycle ergometer, rowing ergometer).
Sponsors
Louis Stokes VA Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Lower limb paralysis due to SCI or other neurological disorder * Greater than 18 years of age * Innervated and excitable lower extremity muscles
Exclusion criteria
* Females that are pregnant * Ventilator dependent * Current pressure injuries that would be exacerbated by exercise * History of spontaneous fractures * Cardiovascular or pulmonary disease that would limit the ability to exercise * Uncontrolled diabetes or hypertension * Large body frame that would prevent participant from comfortably fitting the exercise equipment * Any other medical or psychological condition that would be a contraindication to participating in an exercise program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Exercise Time | At enrollment and end of treatment at 18 weeks or 36 sessions. | Amount of time in minutes an individual is able to continuously exercise |
| Electrically Stimulated Muscle Strength | At enrollment and end of treatment at 18 weeks or 36 sessions. | Electrically stimulated knee extension strength in Newton-meters |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Exercise Power | At enrollment and end of treatment at 18 weeks or 36 sessions. | Average power in watts produced during exercise |
Countries
United States
Contacts
CONTACTMaura Malenchek, PTA
Outcome results
None listed