Stroke
Conditions
Keywords
stroke, aphasia, AVC
Brief summary
In France, stroke affects 150,000 people annually and is the leading cause of acquired disability in adults; 10-12% of patients exhibit mild post-stroke aphasia, a condition defined by language difficulties. Few studies describe mild post-stroke aphasia, and none characterize the impairment of linguistic executive control in this population; consequently, its prevalence remains unknown. To date, the role of linguistic executive control in mild aphasia remains an open question. The aim of this project is to investigate linguistic executive control impairment in stroke survivors with mild aphasia, provide an initial estimate of its prevalence, and demonstrate its interactions with other linguistic and communicative aspects, as well as with executive and attentional functions.
Interventions
DIAGNOSTIC_TESTNeuropsychological tests
Patients undergo neuropsychological tests, the order of which will be randomized.
DIAGNOSTIC_TESTSpeech-language assessments
Patients will undergo speech-language assessments, with the order of the tests randomized.
Sponsors
University Hospital, Toulouse
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patient who has experienced a first ischemic stroke resulting in clinical symptoms within the last 3 months and is receiving care in the Physical Medicine and Rehabilitation department. * Score ≤ 31 on the conversational speech observation scale of the MEC test (Montreal Protocol for the Evaluation of Communication). * Patients with a BDAE score ≥ 3 (Boston Diagnostic Aphasia Examination - French version, Mazaux J.-M. \[1990\]); this score is the gold standard in aphasiology. * Native French-speaking patient capable of understanding oral or written instructions.
Exclusion criteria
* Patients exhibiting behavior or a clinical condition incompatible with test administration, as assessed by the clinician. * Known major visual, auditory, or motor impairments incompatible with test performance. * Known neurodegenerative and/or neurodevelopmental disorders. * Known social cognition disorders (e.g., ASD).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure the proportion of patients with mild post-stroke aphasia exhibiting deficits in linguistic executive control within three months of a first stroke | 7 days after the inclusion | CATEX score result (deficit score if below the mean value minus 1.65 times the standard deviation) |
Secondary
| Measure | Time frame |
|---|---|
| Identification of patients' cognitive-linguistic impairment profiles based on cognitive test scores | 7 days after the inclusion |
| Identification of patients' cognitive-linguistic impairment profiles based on stroke location using factor analysis | 7 days after the inclusion |
| Study of the correlation between linguistic executive control (CATEX score) and the score of the test evaluating gnosies | 7 days after the inclusion |
| Study of the correlation between executive control of language (CATEX score) and the score of the test evaluating access to the lexical stock | 7 days after the inclusion |
| Study of the correlation between linguistic executive control (CATEX score) and the score of the test evaluating access to the semantic system | 7 days after the inclusion |
| Study of the correlation between linguistic executive control (CATEX score) and the score of the test evaluating non-verbal executive control | 7 days after the inclusion |
Countries
France
Contacts
CONTACTElodie GUILLOUET
Outcome results
None listed