Autism, Prematurity
Conditions
Keywords
autism, prematurity, eye tracking biomarkers
Brief summary
This is a single center, intervention study of integrating the eye-tracking (ET) biomarker battery into the existing autism evaluation process at the Riley Early Years Program (EYP). Eligible participants referred for autism testing through EYP will undergo a traditional comprehensive diagnostic assessment by an EYP clinical psychologist.
Interventions
DEVICEEye-tracking device
Eye-tracking device for autism detection
Sponsors
Indiana University
Indiana University Health
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
14 Months to 48 Months
Healthy volunteers
No
Inclusion criteria
* Children born at \<37 weeks' gestational age who are 14-48 months old at time of referral * Ambulatory (i.e., cruising, walking) * Without significant visual impairment * Referred for autism testing through EYP (i.e. medium- or high-risk M-CHAT-R/F screening result at 16-22 months corrected age or by referral to Early Years based on caregiver or provider concern for autism)
Exclusion criteria
* Non-English-speaking participants and families.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with usable eye-tracking biomarker data | Day 1 | The number of participants from whom usable eye-tracking biomarker data is collected will be totaled. |
| Number of participants with suspected autism | Day 1 | The number of participants whose eye-tracker data suggest a potential autism diagnosis will be totaled. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Caregiver attitudes towards use of the eye-tracking device | Day 1 | Caregiver attitudes will be measured toward healthcare devices form. Caregivers will rate their openness to the use of devices or computer programs in medical care and how important the details of using these devices are to them. Participants will respond to questions on a 5 point Likert scale from "Not Important" to "Extremely Important." |
| Individual and Family Predictors (IFP) | Day 1 | Sociodemographic familial history and medical history information for the infant participant will be collected. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORPyone David, MD
Indiana University
PRINCIPAL_INVESTIGATORRebecca McNally Keehn, PhD
Indiana University
PRINCIPAL_INVESTIGATOREdgardo Szyld, MD
Indiana University
Outcome results
None listed