Hypertension, Hypertension (HTN), Artery Disease, Target Organ Damage
Conditions
Keywords
hypertension, common carotid artery, renal artery, femmoral artery, vascular resistant
Brief summary
To evaluate both sides of the common carotid artery, renal artery, and femoral artery in Hypertension patient that cause of systemic arterial hypertension and/or the effects of target organ damage, both structural and functional markers.
Detailed description
The study of the first degree, both sides in some of the aortic branch group, the effect and/or cause of systemic arterial hypertension compared to normotension. According to the theory of systemic arterial hypertension, the arterial resistance and high blood volume flow causing systemic arterial hypertension, the cause of arterial resistance and high blood volume flow evaluation may trace back to the possible actual cause of systemic arterial hypertension by backward investigation. Despite the fact that target organ damage is the crucial maneuver of hypertension evaluation, both sides of the common carotid artery, renal artery, and femoral artery may cause systemic arterial hypertension and may imply that feasible to predict the end organ of stroke, ESRD, and amputated-type arterial occlusion, respectively. This study belongs to 2 questions 1. Can the main aortic branch be evidence of a cause of systemic arterial hypertension following high resistance and/or high fluid flow by theory? 2. Can the main aortic branch be a marker of evidence of endpoint organ damage?
Interventions
Radiographic diameter in cm. of each side of one of Common Carotid Artery, Renal Artery and Femoral Artery
Any kind of radiographic measurement of Peak Systolic Velocity and/or End Diastolic Velocity (cm/s)
Sponsors
Study design
Eligibility
Inclusion criteria
* Adults ≥18 years with diagnosed hypertension by a clinician, both untreated and treated, including successfully treated participants. * Imaging evidence of at least 1 list of * Common carotid artery * Renal artery * Femoral artery
Exclusion criteria
* Fatal pathology and imaging * Pediatric or pregnant participants * Small vessel angiogram * Intravascular endoscopy * Intra-operative estimation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Median of diameter of common carotid artery, renal artery and femoral artery in hypertension patients. | 1 years | Radiographic measurement includes ultrasonography, CT/MR imaging, and intravascular contrast media imaging that measure the diameter in cm. unit of any side of common carotid artery and/or renal artery and/or femoral artery in hypertension patients. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Common Carotid Artery Function | 1 year | Any kind of radiographic measurement one of Peak Systolic Velocity (cm/s) or End Diastolic Velocity (cm/s) of any side of Common Carotid Artery |
| Renal Artery Function | 1 year | Any kind of radiographic measurement one of Peak Systolic Velocity (cm/s) or End Diastolic Velocity (cm/s) of any side of Renal Artery |
| Femoral Artery Function | 1 year | Any kind of radiographic measurement one of Peak Systolic Velocity (cm/s) or End Diastolic Velocity (cm/s) of any side of Femoral Artery |
Countries
Thailand