Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular Stroke

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07756775

Enrollment

200

Registered

2026-08-11

Start date

2026-07-20

Completion date

2027-03-20

Last updated

2026-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid Artery Stenosis (Symptomatic and Asymptomatic), Ischemic Stroke, Transient Ischemic Attack

Brief summary

This prospective observational study aims to compare the diagnostic performance of non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography in the evaluation of carotid artery disease among patients with ischemic cerebrovascular stroke or transient ischemic attack. A total of 200 adult patients presenting to Sohag University Hospital will undergo both imaging modalities. The study will assess the agreement between NC-MRA and carotid Doppler in detecting and grading carotid artery stenosis according to the NASCET criteria, with the goal of evaluating the clinical utility of each technique and optimizing imaging strategies for the assessment of cerebrovascular stroke.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults aged 18 years or older. * Clinically diagnosed ischemic stroke or transient ischemic attack (TIA). * Imaging performed within 7-14 days of symptom onset. * Hemodynamically stable and suitable for magnetic resonance imaging (MRI). * Able and willing to provide written informed consent.

Exclusion criteria

* Hemorrhagic stroke. * Previous carotid artery stenting. * Contraindications to MRI, including: * Non-MRI-compatible pacemakers or other MRI-incompatible implants. * Cochlear implants. * MRI-incompatible metallic orthopedic implants. * Severe claustrophobia.

Design outcomes

Primary

Measure	Time frame	Description
Internal Carotid Artery Stenosis Grade (according to NASCET criteria) assessed by Non-contrast Magnetic Resonance Angiography and Carotid Doppler ultrasonography.	At the baseline imaging visit (within 7-14 days of symptom onset).	Internal carotid artery stenosis grade in patients with ischemic stroke or transient ischemic attack determined according to the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria using non-contrast magnetic resonance angiography and carotid Doppler ultrasonography. The stenosis grades obtained by the two imaging modalities will be compared.

Countries

Egypt

Contacts

CONTACTMohamed Saad Gad

mohsaadgad@gmail.com+201112435154

STUDY_CHAIRMohamed Tharwat Mahmoud, Professor

Sohag University

Outcome results