Placenta Accreta, Third Trimester
Conditions
Keywords
placenta accreta
Brief summary
Primary Objective: To determine the optimal cutoff values of the ultrasound score for different PAS subtypes (no PAS, placenta accreta, placenta increta, and placenta percreta). To evaluate the diagnostic accuracy of the novel Ultrasound Scoring System in predicting the severity of Placenta Accreta Spectrum (PAS) (placenta accreta, increta, and percreta). Secondary Objective: * To correlate the novel ultrasound score with intraoperative findings (considered the gold standard) during cesarean delivery, including the degree of placental invasion and the need for surgical interventions (hysterectomy, bladder repair). * To assess the relationship between the novel ultrasound score and postoperative complications, such as: * Requirement for hysterectomy * Bladder or bowel injury * Blood transfusion requirement * ICU admission rates * To explore the potential for integrating the Ultrasound Scoring System with other clinical indicators (e.g., patient age, parity, and history of cesarean sections) to enhance the predictive accuracy for PAS.
Detailed description
Primary Objective: * To determine the optimal cutoff values of the ultrasound score for different PAS subtypes (no PAS, placenta accreta, placenta increta, and placenta percreta). * To evaluate the diagnostic accuracy of the novel Ultrasound Scoring * System in predicting the severity of Placenta Accreta Spectrum (PAS) (placenta accreta, increta, and percreta). Secondary Objective: * To correlate the novel ultrasound score with intraoperative findings (considered the gold standard) during cesarean delivery, including the degree of placental invasion and the need for surgical interventions (hysterectomy, bladder repair). * To assess the relationship between the novel ultrasound score and postoperative complications, such as: * Requirement for hysterectomy * Bladder or bowel injury * Blood transfusion requirement * ICU admission rates * To explore the potential for integrating the Ultrasound Scoring System with other clinical indicators (e.g., patient age, parity, and history of cesarean sections) to enhance the predictive accuracy for PAS.
Interventions
None listed
Sponsors
Sohag University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Pregnant women aged 18 to 45 years. * Gestational age ≥28 weeks at the time of enrollment. * Diagnosed Placenta Previa with a history of: * One or more previous cesarean sections * Uterine scarring due to previous surgery as (myomectomy, D\&C, Metroplasty). * Singleton pregnancy.
Exclusion criteria
* Women with multiple pregnancies (twins, triplets, etc.). * Pregnancies complicated by acute medical conditions (e.g., heart failure, uncontrolled diabetes). * Prior history of Blood diseases. (other than those related to pregnancy). * Women who refuse to participate or withdraw consent during the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| degree of placental invasion and inability to conserve the uterus | 1 week | Need for Hysterectomy: Determined by the degree of placental invasion and inability to conserve the uterus \&Histopathogy confirmation. Bladder Injury: Recorded if any injury occurs during the procedure. Blood Transfusion Requirement: Amount of blood transfused intraoperatively. ICU Admission: Postoperative ICU admission requirement due to hemorrhage or other complications. |
Contacts
CONTACTAhmed Adel Khalifa, resident
Outcome results
None listed