Post Operative Pain, Acute
Conditions
Keywords
irreversible pulpitis, postoperative pain, visual analogue score, dexamethasone, buccinator injection, buccal infiltration
Brief summary
The aim of this randomized clinical trial to evaluate the effect of dexamethasone in two different techniques on postoperative pain by dividing patients randomly into three groups: * Group I: buccinator injection of dexamethasone. * Group II: buccal infiltration of dexamethasone. * Group III (Control): IANB using local anesthesia only post operative pain will be evaluated subjectively by patients by VAS score after procedure immediately and follow up for 12, 24 and 72 hours and frequency of analgesic intake
Detailed description
the previous studies used dexamethasone with LA to prolong the duration of nerve block , Dexamethasone is used in reducing intraoperative endodontic pain the study main aim is to overcome the problem of severe postoperative pain after endodontic treatment in patients with acute irreversible pulpitis by evaluating the effect of dexamethasone in two different techniques by giving dexamethasone injection of buccinator muscle, or dexamethasone as buccal infiltration, and comparing the results with inferior alveolar nerve block using local anesthesia only. pain score evaluated using VAS score preoperatively and postoperatively with different anesthetic techniques after endodontic treatment.and their effet on frequency of analgesic intake
Interventions
8mg/2ml injected slowly 30 sec for 1ml as single injection before the endo treatment
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Intervention model description
• patients will be randomly divided into three groups: * Group I: will receive buccinator muscle injection of dexamethasone((2ml of 8mg) after inferior alveolar nerve block (IANB) * Group II: will receive buccal infiltration of dexamethasone (2ml of 8mg) after (IANB) * Group III (Control): will receive IANB by anesthetic 4% articaine HCl with 1:100,000 ratio of epinephrine only.
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Both genders * Older than age of (18 to 60) years * Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study * Having a mandibular molar tooth with vital pulp * These patients were also suffering from symptomatic irreversible pulpitis ,intermittent or continuous sharp pain that lasts longer after removal of the stimulus * Patients with moderate to severe symptoms VAS≥4
Exclusion criteria
* Vulnerable group; pregnant females, mentally ill and diseased patientsetc.… * Patients irritable to local anesthesia * Patients who are supposed to take plain anesthesia * Use of analgesic or antibiotic within 6 hours before the visit * Absence of bleeding in the pulp chamber during cavity preparation * Severe periodontal disease b- Patients' randomization, allocation and blinding:
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| visual analogue score (VAS) from 0 to 10 | postoperative 72 hours | VAS preoperative ,immediately postoperative,12hrs,24hrs,72hrs |
Countries
Egypt
Contacts
STUDY_DIRECTORMahmoud Fahim, lecturer
Faculty of Dentistry, Ain Shams University
STUDY_CHAIRsalma masoud, master student
Faculty of Dentistry, Ain Shams University
PRINCIPAL_INVESTIGATORAbeer Abdelhakim Elgendy, Professor
Faculty of Dentistry, Ain Shams University
Outcome results
None listed