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Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment

Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment: A Split Mouth Randomized Controlled Trial

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07753512
Enrollment
34
Registered
2026-08-07
Start date
2027-01-15
Completion date
2028-06-15
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crowding of Teeth, Malaligned Teeth

Keywords

white spot lesions, orthodontic adhesives

Brief summary

The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.

Detailed description

The aim of this study is to compare the number of white spot lesions that appear around bonded brackets between self-etch and one-step bonding systems using visual examination and to compare amount of demineralisation using DIAGNOdent scores.

Interventions

COMBINATION_PRODUCTSelf-etch adhesive

Self-Etch adhesive used for two step bonding of bracket placement.

COMBINATION_PRODUCTOne-Step Adhesive

Placement of bracket using one-step adhesive system.

COMBINATION_PRODUCTConventional Bonding Technique

Bonding brackets using three step conventional technique; etchant , bonding agent, composite adhesive

Sponsors

Foundation University Islamabad
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
12 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* healthy patients 12-30 yrs * patients undergoing fixed appliance treatment with full mouth bonding * presence of at least 7 accessible teeth * no cavitated lesion at time of bond up

Exclusion criteria

* patients with chronic or systematic diseases * patients with fluorosis or enamel defects * presence of fixed prosthesis * patients on medications which could alter salivary flow * patients with history of salivary gland disease

Design outcomes

Primary

MeasureTime frameDescription
Number of white spot lesionsFrom bracket placement to 6 months after placement.
Demineralisation of bonded teethFrom date of bracket placement to 6 months of treatmentAmount of demineralisation around brackets measured

Countries

Pakistan

Contacts

CONTACTEmaan Ahsin
emaan.ahsin@fui.edu.pk92 3065843663
CONTACTRozina Nazir
rozina.nazir@fui.edu.pk923215376612

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 11, 2026