Molar Incisor Hypomineralization
Conditions
Brief summary
Background: Resin infiltration often shows unpredictable outcomes in teeth affected by molar incisor hypomineralisation (MIH) due to variable enamel porosities, hypermineralised surface layers, and elevated protein content. Different pretreatment modalities alongside modified resin infiltration protocols have been suggested to enhance aesthetic masking and the required resin infiltration time. Aim: To compare the effectiveness of transillumination-guided 5.25% NaOCl pretreatment following macroabrasion, with macroabrasion alone, each with 10-second hydrochloric acid (HCl) etching intervals, on aesthetic masking and resin infiltration time required in MIH-affected incisors.
Interventions
OTHERmacroabrasion followed by oxidative pretreatment
Fine-grit aluminum oxide finishing stone under water coolant, using a high-speed handpiece to remove the superficial enamel layer, then 5.25% sodium hypochlorite will be applied to the labial lesion surface and agitated with a microbrush for one minute, then rinsed for 20 seconds.
OTHERmacroabrasion alone
Fine-grit aluminum oxide finishing stone under water coolant, using a high-speed handpiece to remove the superficial enamel layer,
Sponsors
Alexandria University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
8 Years to 13 Years
Healthy volunteers
No
Inclusion criteria
* Healthy children with MIH-related mild white creamy opacities on permanent incisors, code 1 according to the European Academy of Paediatric Dentistry (EAPD) criteria. * Clinically detectable isolated lesions (whether homogeneous or heterogeneous on the incisal and middle thirds of the buccal surface of the selected teeth. * Patients with score 3 (positive) or score 4 (definitely positive) according to Frankl behavioral rating scale * Parents or legal guardians accepting to sign a written consent and join the study
Exclusion criteria
* MIH-affected permanent incisors with post-eruptive enamel breakdown, cavitated lesions, restorations, or previously treated with surface layer removal or remineralising agents in the previous six months. * Children with an allergy history
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in aesthetic masking effectiveness | up to 6 months | Transillumination images (T0, Tx, Tmax) will be imported into ImageJ (National Institutes of Health, MD, USA), resized, and superimposed to align the labial surfaces. The labial surface and opacity will be manually outlined to measure their respective surface areas. The opacity area ratio will then be calculated as: R = (AO × 100) / AL, where AO is the opacity area and AL is the total labial surface area |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in color stability | up to 6 months | 2\. Color stability will be calculated based on the changes in the CIE L\*a\*b\* values over time. The color difference (ΔE) between timepoints will be obtained using the following formula: ΔE=√\[(ΔL)2 + (Δa)2 + (Δb)2\]. |
| Changes in the patient-reported SCASS scores | up to 6 months | The Schiff Cold Air Sensitivity Scale (SCASS) was used to assess patient-reported dentin hypersensitivity following an air stimulus. The scale ranges from 0 to 3, where 0 indicates no response to the stimulus, 1 indicates a response without requesting discontinuation, 2 indicates a response accompanied by a request to stop the stimulus or withdrawal from it, and 3 indicates a painful response with an immediate request to discontinue the stimulus and/or marked painful behavior. Higher SCASS scores indicate greater dentin hypersensitivity. |
| change in patient satisfaction | up to 6 months | 5-point Likert scale for the patients' satisfaction. higher socres mean more satisfaction |
Countries
Egypt
Contacts
CONTACTMaryam AbdulAziz
Outcome results
None listed