Skip to content

Perfusion Index and Spinal Hypotension in Day-Case Knee Arthroscopy

Predictive Value of Baseline Perfusion Index for Spinal Anesthesia-Induced Hypotension in Healthy Patients Undergoing Knee Arthroscopy: A Prospective Observational Trial

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07747441
Enrollment
150
Registered
2026-08-05
Start date
2026-08-06
Completion date
2026-12-28
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Spinal, Arthroscopy, Hypotension, Spinal Anesthesia Induced Hypotension

Keywords

Perfusion Index, Spinal Anesthesia, Hypotension, Knee Arthroscopy

Brief summary

This prospective observational study aims to investigate the role of the baseline perfusion index (PI) in predicting spinal anesthesia-induced hypotension (SAIH) in ASA I-II patients undergoing day-case knee arthroscopy. Spinal anesthesia is a widely preferred technique for lower extremity surgeries, including knee arthroscopy. However, sympathetic blockade during spinal anesthesia frequently leads to significant hemodynamic instability, particularly hypotension, which can result in adverse perioperative outcomes. While age and baseline blood pressure are traditional risk factors, they often fail to accurately predict the onset of hypotension in healthy populations. The perfusion index (PI), a non-invasive parameter measured via pulse oximetry, reflects peripheral vascular tone and baseline sympathetic activity. An elevated baseline PI indicates baseline vasodilation and a higher susceptibility to sympathectomy, potentially offering an early and non-invasive prediction of SAIH before the hemodynamic collapse occurs. The primary outcome of the study is the incidence of spinal anesthesia-induced hypotension (defined as a mean arterial pressure \< 65 mmHg or a decrease in systolic blood pressure \> 25% from baseline). Secondary outcomes include the onset time of sensory block, and intraoperative ephedrine and fluid requirements.

Interventions

None listed

Sponsors

Ankara Etlik City Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Between the ages of 18-65 * Having an ASA Score of I-II * Including data collection of parts that underwent knee arthroscopy

Exclusion criteria

* Patients under 18 and over 65 years of age * Patients with ASA Score III and above

Design outcomes

Primary

MeasureTime frameDescription
Spinal anesthesia-induced hypotensionDuring the surgeryDefined as a mean arterial pressure \< 65 mmHg or a decrease in systolic blood pressure \> 25% from baseline

Secondary

MeasureTime frameDescription
Investigation of Sensory Block KineticsPeriproceduralTime to reach the T10 sensory dermatome
Vasopressor ConsumptionDuring the surgeryTotal amount of rescue vasopressor (Ephedrine) consumed to treat hypotension during the intraoperative period

Countries

Turkey (Türkiye)

Contacts

CONTACTİbrahim MD Topcu, MD
ibrahimtpc78@gmail.com05437860316
CONTACTMusa Ass. Prof Zengin, Ass. Prof
musazengin@gmail.com05071302750

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 11, 2026