Novel Abdominal Compression Positioning Technique for Respiratory Motion Management in Liver Tumors

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07745153

Enrollment

120

Registered

2026-08-04

Start date

2025-01-01

Completion date

2026-07-23

Last updated

2026-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carcinoma, Hepatocellular, Liver Neoplasms

Keywords

SBRT, liver tumor, abdominal compression

Brief summary

1. Research Background The background of this study centers on stereotactic body radiation therapy (SBRT), an advanced form of radiotherapy that is short in duration, highly effective, and easy for patients to comply with. However, even small breathing movements can reduce its precision. Abdominal compression devices have been proven to reduce respiratory motion and are now widely used in clinical practice. This study aims to determine whether a novel abdominal compression positioning technique can control tumor motion as effectively as current abdominal compression devices, whether it works better than traditional thermoplastic masks, and whether it can offer meaningful benefits to patients undergoing radiotherapy. These questions remain to be explored. 2. Study Objectives The purpose of this study is to investigate how different immobilization devices affect the respiratory motion of liver tumors, in order to better assist with target delineation and the delivery of stereotactic body radiation therapy.

Detailed description

This study is a single-center, ambidirectional observational study.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Voluntarily signed informed consent. Age ≥ 18 years. Patients who require radiotherapy for liver cancer, as determined by the treating physician. Life expectancy \> 3 months.

Exclusion criteria

* Discontinuation of radiotherapy or failure to complete the radiotherapy plan as prescribed. Presence of serious complications or comorbidities that may affect safety.

Design outcomes

Primary

Measure	Time frame	Description
Tumor respiratory motion	Within 1 week after completion of radiotherapy	Tumor respiratory motion amplitude
Liver respiratory motion	Within 1 week after completion of radiotherapy	Liver respiratory motion amplitude

Secondary

Measure	Time frame	Description
Local control rates	Within one year after the completion of radiotherapy	Status of local tumor control

Countries

China

Outcome results