Relationship Between Frontal QRS-T Angle and Collateral Circulation in Coronary Artery Chronic Total Occlusion

Frontal QRS-T Angle as an Electrocardiographic Marker for Collateral Circulation in Coronary Artery Chronic Total Occlusion

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07743437

Enrollment

100

Registered

2026-08-03

Start date

2026-08-01

Completion date

2028-09-01

Last updated

2026-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Total Occlusion (CTO), Frontal QRS-T Angle

Keywords

frontal QRS-T angle, Chronic total occlusion

Brief summary

• Aim of the work: To examine the relationship between collateral circulation and the frontal QRS-T angle in patients with chronic total occlusion (CTO)

Detailed description

i. Study Objectives 1. Primary Objective: • To examine the relationship between coronary collateral circulation and the electrocardiographic frontal QRS-T angle in patients diagnosed with chronic total occlusion (CTO). 2. Secondary Objectives: * To identify other independent clinical and laboratory predictors (such as serum albumin levels and neutrophil counts) associated with an increased frontal QRS-T angle in patients with CTO. * To compare echocardiographic parameters (such as left ventricular ejection fraction and left ventricular dimensions) between patients with a normal QRS-T angle and those with an increased QRS-T angle.

Interventions

DIAGNOSTIC_TEST12-lead Electrocardiogram (ECG) and Coronary Angiography

A 12-lead ECG is performed to calculate the frontal QRS-T angle, and coronary angiography is performed to evaluate the coronary collateral circulation using the Rentrop Classification.

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients undergoing diagnostic coronary angiography due to stable angina persisting for a minimum duration of three months. * Patients diagnosed with total occlusion in at least one coronary artery, assessed to have chronic total occlusion (CTO) based on clinical and angiographic findings.

Exclusion criteria

* Patients presenting with malignancies, atrial fibrillation, connective tissue disorders, hepatic failure, or renal failure. * A documented history of cardiac pacemaker implantation, prior bypass surgeries, or surgical valve replacements. * Congenital heart anomalies. * Patients receiving pharmacological interventions that affect ventricular repolarization (other than beta-adrenergic antagonists). * Individuals exhibiting abnormal electrolyte levels at the time of admission.

Design outcomes

Primary

Measure	Time frame	Description
correlation between frontal QRS-T angle and collateral circulation in CTO patients	baseline ( at the time of the diagnosis )	• To examine the relationship between coronary collateral circulation and the electrocardiographic frontal QRS-T angle in patients diagnosed with chronic total occlusion (CTO).

Countries

Egypt

Contacts

CONTACTTarek Yaser

tarek.18313588@med.aun.edu.eg+201005094712

CONTACTHosam Hasan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 5, 2026