Periodontitis
Conditions
Brief summary
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on targeted metabolomics in gingival crevicular fluid
Detailed description
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis. All the 60 patients with periodontitis are assessed for clinical, periodontal, and gingival crevicular fluid following of minimally invasive approach MINST or Q-SI (quadrantwise). Measurements are taken before and after initial periodontal treatment in the periodontal subjects.
Interventions
OTHERProbing depth reduction
Probing depth reduction in millimetres before and after treatment
Sponsors
University of Catania
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of Periodontitis
Exclusion criteria
* Periodontal treatment during the last 6 months * Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probing pocket depth | 6 months | Reduction in Probing Pocket Depth after treatment |
Countries
Italy
Contacts
CONTACTGaetano Isola
Outcome results
None listed