Low Energy, Low Libido, Low Sperm Quality, Low Testosterone, Male Infertility
Conditions
Brief summary
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the test product daily in the morning with their first meal. Participants will complete questionnaires at Baseline, Month 1, Month 2, and Month 3. Semen analysis will be conducted at home at Baseline and Month 3, and blood testing will be performed at a local Labcorp location at Baseline and Month 3. The primary focus is on sperm quality parameters and testosterone levels, while secondary endpoints capture participants' perceptions of changes in reproductive and sexual health, including energy and libido.
Interventions
DIETARY_SUPPLEMENTWeNatal For Him Supplement
All participants take 3 capsules of the WeNatal For Him supplement daily in the morning with their first meal for 3 months.
Sponsors
WeNatal
Citruslabs
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Be male * Be aged 30+ * Anyone currently experiencing issues regarding low energy and low libido * Anyone who is generally healthy - does not live with any uncontrolled chronic disease * Willing to stop taking any other products or prescription medication, herbal remedies, or supplements for the duration of the study that target fertility, reproductive health, and sexual health * Not planning on introducing any products or any new prescription medication, herbal remedies, or supplements that target male fertility, reproductive health, or sexual health for the study duration * Resides in the United States * Not currently partaking in another research study and will not be partaking in any other research study for the next 3 months and at any point during this study's duration * Willing to provide a semen sample via masturbation * Willing to abstain from ejaculation for a minimum of 48 hours and a maximum of 5 days before providing the semen sample * Willing to abstain from marijuana products during the entire study duration
Exclusion criteria
* Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders * Anyone who has ever taken supplemental testosterone * Anyone planning to undergo any surgeries or invasive treatments for the study duration * Anyone who has had a major illness in the last 3 months * Anyone currently undergoing any type of fertility treatment * Anyone with any allergies or sensitivities to any of the study product ingredients * Anyone unwilling to follow the study protocol * Anyone taking anticoagulant or 'blood thinner' medication * Anyone undergoing chemotherapy * Anyone taking insulin or diabetes medication * Anyone who drinks heavily (i.e. 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men) * Anyone with a history of substance abuse * Anyone who is currently a smoker or has been a smoker in the past 3 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Testosterone (Free and Total) | Baseline and Month 3 | Assessed via blood test at a local Labcorp location measuring free and total testosterone levels |
| Change in Sperm Volume | Baseline and Month 3 | Assessed via at-home semen analysis using the Fellow Semen Analysis kit |
| Change in Sperm Concentration | Baseline and Month 3 | Assessed via at-home semen analysis using the Fellow Semen Analysis kit |
| Change in Sperm Count | Baseline and Month 3 | Assessed via at-home semen analysis using the Fellow Semen Analysis kit |
| Change in Sperm Motility | Baseline and Month 3 | Assessed via at-home semen analysis using the Fellow Semen Analysis kit |
| Change in Total Motile Count | Baseline and Month 3 | Assessed via at-home semen analysis using the Fellow Semen Analysis kit |
| Change in Sperm Morphology | Baseline and Month 3 | Assessed via at-home semen analysis using the Fellow Semen Analysis kit |
| Change in 25-hydroxy Vitamin D | Baseline and Month 3 | Assessed via blood test at a local Labcorp location |
| Change in hs-CRP | Baseline and Month 3 | Assessed via blood test at a local Labcorp location |
| Change in Homocysteine | Baseline and Month 3 | Assessed via blood test at a local Labcorp location |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Self-Reported Reproductive Health | Baseline, Month 1, Month 2, and Month 3 | Assessed via self-reported questionnaire |
| Change in Self-Reported Energy | Baseline, Month 1, Month 2, and Month 3 | Assessed via self-reported questionnaire |
| Change in Self-Reported Libido | Baseline, Month 1, Month 2, and Month 3 | Assessed via self-reported questionnaire |
Countries
United States
Outcome results
None listed