Cervical Spondylopathy
Conditions
Keywords
anterior cervical discectomy and fusion, Polyetheretherketone, iliac crest
Brief summary
The cervical spine is the most mobile portion of the spine and is more prone to degenerative spine changes like cervical disc herniation, cervical spine stenosis, ossified posterior longitudinal ligament and osteophyte formation. Cervical spondylosis describes a variety of progressive degenerative changes that affect all components of the cervical spine (i.e., intervertebral discs, facet joints, Luschka joints, ligamentum flavum, and lamina). This is a normal aging process that affects most people in their 50's. Due to its stability, ACDF (anterior cervical discectomy and fusion) employing an iliac crest auto-graft is regarded as best, but it carries significant donor-site morbidity, hematoma formation, infection and pain etc. These morbidities leads to development of newer techniques, such as a PEEK cage. This technique lacks donor site morbidity but it is not cost-effective. The purpose of this study is to compare bony fusion between two of the most common fusion grafts: iliac crest auto-graft and PEEK(Polyetheretherketone) cage allograft, among patients undergoing ACDF in the Neurosurgical facility of Services Hospital, Lahore.
Interventions
PROCEDUREAnterior Cervical Dissectomy and Fusion using Iliac crest autograft
After receiving written informed consent, name, age, gender, and sickness duration, demographic factors were also documented. 21 participants underwent bone transplant, plating, and ACDF (anterior cervical discectomy and fusion)
DEVICEPolyetheretherketone (PEEK) cage
In group B, PEEK (Polyetheretherketone) cage and plating were used
Sponsors
Services Hospital, Lahore
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
In our study, patients were included with an age of 20- 60 years, both male and female, and having one level of disc disorder between C3-C7 with radiculopathy/myelopathy, no previous ACDF Surgery, and Cervical Spine traumatic injury.
Exclusion criteria
Patients who had previous cervical spine surgery, having more than one level of pathology, patients who needed posterior instrumentation, having infection/Caries Spine/Osteomyelitis etc. and having malignancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Trabecular Bone Formation and Bridging Bone Formation | 6 Months | Trabecular bone is the formation of bone between graft and end plates of superior and inferior vertebrae.It was noted at 1, 3 and 6th Month. |
| Motion on Flexion-Extension X-rays | 6 Months | Motion of the spinous process of \<2mm is marked as fused, while a distance of \> 2 mm between spinous processes on flexion and extension X-rays is marked as unfused. |
| Disc Height Score | 6 Months | Disc height was observed as distance between endplates and \>25% reduction in disc height from postoperative X-rays were noted as unfused |
Countries
Pakistan
Outcome results
None listed