Fracture
Conditions
Brief summary
The goal of this observational study is to establish a standardized multicenter cohort and develop and validate clinically interpretable models for perioperative risk stratification, brain-state risk prediction, objective pain assessment, sleep-pain-delirium association analysis, and longer-term prognosis.The main questions it aims to answer are: Can clinically interpretable predictive models be developed for perioperative risk stratification and brain-state changes? What are the associations among objective pain measures, sleep quality, and postoperative delirium? Are these perioperative factors associated with longer-term patient outcomes? This is a multicenter cohort study without a separate comparator group. Participants will undergo routine perioperative clinical assessments and standardized follow-up evaluations according to the study protocol.
Detailed description
Approximately 4,000-4,500 participants: 2,800-3,000 retrospective records and 1,200-1,500 prospectively enrolled participants
Interventions
None listed
Sponsors
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients who have hip fracture or another eligible fracture requiring perioperative management and who undergo, or are scheduled to undergo, fracture surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality within 365 days after fracture surgery | 365 days after fracture surgery |
Outcome results
None listed