Middle Ear Optical Coherence Tomography Imaging and Vibrometry in Patients With Hearing Loss

OCT Imaging and Vibrometry in Patients With Hearing Loss: A Pilot Study

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07732920

Enrollment

500

Registered

2026-07-29

Start date

2026-08-01

Completion date

2028-08-31

Last updated

2026-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Conductive Hearing Loss, Sensorineural Hearing Loss

Keywords

OCT, vibrometry

Brief summary

This study involves imaging ears with hearing loss with a new system that allows the user to see the middle ear bones and measure their movement in response to sound.

Detailed description

This study is an exploratory clinical investigation to obtain pilot imaging and vibrometry data in patients with various hearing loss aetiologies and to identify qualitative and quantitative features associated with specific pathologies. The data collected in this study is intended to support future investigations into the accuracy of the system in diagnosing specific middle ear disorders.

Interventions

OTHEROCT - clear

OCT imaging and vibrometry

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adults ages 18+ Conductive or sensorineural hearing loss -

Exclusion criteria

Adults with normal hearing Children Subjects unable to understand Informed consent \-

Design outcomes

Primary

Measure	Time frame	Description
Vibrometry (Ossicular mobility in mm/s/Pa)	2 years	Optical Coherenece Tomography vibrometry measures of ossicular mobility for the umbo and incus in mm/s/Pa for 6 frequencies of 500, 750, 1000, 1500, 2000 and 3000 Hz
Standard audiometry--threshold measurement in dBHL	2 years	Standard pure tone and bone conduction audiometry--measurement of acoustic thresholds for air and bone conductive stimuli at 250, 500, 1000, 2000, 3000 , 4000, 6000 and 8000 Hz
Standard tympanometry--measurement of acoustic immittance in daPa	2 years	Standard tympanometric testing of ear canal volume and middle ear immittance

Countries

Canada

Contacts

CONTACTCatherine L Creaser

catherine.creaser@zeiss.com902-891-2891

CONTACTSite operations manager

carmen.mcknight@zeiss.com902-440-2895

PRINCIPAL_INVESTIGATORDavid P Morris, MD

Nova Scotia Health Authority

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 30, 2026