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Effect of an Eight Week Dietary Intervention of Pecans on Cardiometabolic Parameters and Serum Cytokines in Individuals With Obesity or Overweight

Effect of an Eight Week Dietary Intervention of Pecans on Cardiometabolic Parameters and Serum Cytokines in Individuals With Obesity or Overweight

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07732816
Enrollment
22
Registered
2026-07-29
Start date
2016-10-17
Completion date
2018-10-17
Last updated
2026-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity & Overweight

Keywords

obesity, monounsaturated fatty acids, pecans, cardiometabolic health, inflammation, dietary intake

Brief summary

You are invited to participate in a research study being conducted by Karen Gibson, Maria Morgan-Bathke, Dana Swope, Grace Huebner, Rebecca Brannan, Samuel McCormick at Viterbo University. The purpose of this research is to determine the effectiveness of using nuts and avocados as a dietary intervention on improving fasting blood glucose, lipid profile, energy expenditure, and body composition on pre-diabetic individuals compared to a control group. We hope to learn if a dietary intervention of nuts or avocado can help improve blood sugar, lipid panel and/or body composition. You were selected as a possible participant in this study because you have been diagnosed with pre-diabetes. If you decide to participate, you will be asked to complete an initial two hour appointment, follow the protocol of one of the interventions (one avocado or 1 ½ ounce nuts) and control group with only dietary counseling provided) daily for an eight week period, weekly telephone and/or email nutrition counseling, and attend a final two hour appointment. The food for the intervention (avocados and nuts) will be provided by the researchers and will not need to be purchased by the participants. The initial and final two hour appointments will consist of the following measurements: An overnight fast, blood glucose, cytokine level, and lipid panel tests will be completed by a venous blood draw. Then Maltron scan (to measure body composition, which in non-invasive and uses electrodes on the skin), waist/hip measurements, height/weight, and VioCare food frequency questionnaire will be completed. Following these screening measurements, a COSMED test to determine resting energy expenditure (REE) will be measured. It may take approximately 10 weeks from beginning to completion of this study.

Interventions

OTHERPecan Intervention

1.5 oz of pecans daily

Sponsors

Viterbo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

\- BMI of 25.0-40.0

Exclusion criteria

* BMI below 25.0 or over 40.0 * anyone who works a 3rd shift * pregnant and breastfeeding women * those with pre-existing chronic conditions * those with a latex allergy

Design outcomes

Primary

MeasureTime frameDescription
body composition10 weekspercentage body fat
fasting blood glucose10 weeksfasting blood glucose in mg/dl
weight10 weeksweight in kg
height10 weeksheight in meters
total cholesterol10 weekstotal cholesterol in mg/dl
LDL cholesterol10 weeksLDL cholesterol in mg/dl
HDL10 weeksHDL cholesterol in mg/dl
TG10 weekstriglycerides in mg/dl

Secondary

MeasureTime frameDescription
inflammation10 weekscirculating inflammation via plasma TNF-alpha in pg/ml
anti-inflammatory10 weekscirculating inflammation via plasma IL-10 in pg/ml

Contacts

PRINCIPAL_INVESTIGATORMaria Morgan-Bathke, PhD

Viterbo University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 30, 2026