CAKUT, Congenital Anomalies of the Kidney and Urinary Tract, Congenital Kidney Disease
Conditions
Keywords
CAKUT, Congenital anomalies of the kidney, Urinary Tract Anomalies, Pediatric Nephrology, Children, Egypt, Sohag, Congenital kidney disease
Brief summary
This is an observational study conducted at Sohag University Hospital to assess the clinical presentation, associated anomalies, and short-term outcomes of children diagnosed with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT). The investigators will include children from newborns to 18 years old who are diagnosed with CAKUT by ultrasound or other imaging methods. The study aims to describe how common different types of CAKUT are, what other health problems are associated with them, and what happens to these children during follow-up. No experimental drugs or interventions will be given. The investigators will only collect data from patient medical records and routine follow-up visits. The results of this study will help doctors in Egypt better understand CAKUT and improve early diagnosis and management for children
Detailed description
This is a single-center, observational cohort study conducted at the Pediatric Nephrology Department, Sohag University Hospital, Egypt. Study Population: Children from birth to 18 years diagnosed with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) by prenatal or postnatal ultrasound or other imaging modalities. Data Collection: Demographic data, clinical presentation, laboratory results, imaging findings, and treatment modalities will be collected from medical records. Patients will be followed during routine clinic visits for a minimum of 6 months. Objectives: 1. To determine the frequency and types of CAKUT in our center. 2. To describe associated extra-renal anomalies. 3. To assess short-term renal outcomes and complications. This study does not involve any experimental interventions. All investigations and management will be according to standard hospital protocols.
Interventions
No experimental intervention. Data will be collected from routine clinical care, medical records, and follow-up visits according to standard hospital protocols.
Sponsors
Study design
Eligibility
Inclusion criteria
* All children admitted to Pediatric department, Sohag University Hospital who had a renal ultrasound performed.
Exclusion criteria
1. Files with missing essential data. 2. Children transferred from another hospital without renal US done at our center. 3. Children who died before renal US could be performed. 4. Age \> 18 years 5. Acquired kidney disease not related to congenital anomalies 6. Patient/family refusal to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency and Types of CAKUT | 1 Year | The proportion of different types of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) diagnosed by ultrasound among pediatric patients at Sohag University Hospital. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Associated Extra- renal Anomalies | 1 Year | Frequency of associated congenital anomalies in other organ systems in children with CAKUT. |
| Renal Outcome | 1 Year | Incidence of CKD, hypertension, or need for dialysis/transplant during follow-up period. |
Countries
Egypt